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Structure-guided engineering of a fast genetically encoded sensor for real-time H2O2 monitoring.
Lee JD, Won W, Kimball K, Wang Y, Yeboah F, Evitts KM, Neiswanger C, Schattauer S, Rappleye M, Bremner SB, Chun C, Smith N, Mack DL, Young JE, Lee CJ, Chavkin C, Berndt A. Lee JD, et al. Among authors: mack dl. bioRxiv [Preprint]. 2024 Feb 4:2024.01.31.578117. doi: 10.1101/2024.01.31.578117. bioRxiv. 2024. PMID: 38352381 Free PMC article. Preprint.
Incorporation of sensing modalities into de novo designed fluorescence-activating proteins.
Klima JC, Doyle LA, Lee JD, Rappleye M, Gagnon LA, Lee MY, Barros EP, Vorobieva AA, Dou J, Bremner S, Quon JS, Chow CM, Carter L, Mack DL, Amaro RE, Vaughan JC, Berndt A, Stoddard BL, Baker D. Klima JC, et al. Among authors: mack dl. Nat Commun. 2021 Feb 8;12(1):856. doi: 10.1038/s41467-020-18911-w. Nat Commun. 2021. PMID: 33558528 Free PMC article.
Multi-scale models reveal hypertrophic cardiomyopathy MYH7 G256E mutation drives hypercontractility and elevated mitochondrial respiration.
Lee S, Roest ASV, Blair CA, Kao K, Bremner SB, Childers MC, Pathak D, Heinrich P, Lee D, Chirikian O, Mohran S, Roberts B, Smith JE, Jahng JW, Paik DT, Wu JC, Gunawardane RN, Spudich JA, Ruppel K, Mack D, Pruitt BL, Regnier M, Wu SM, Bernstein D. Lee S, et al. bioRxiv [Preprint]. 2023 Jun 9:2023.06.08.544276. doi: 10.1101/2023.06.08.544276. bioRxiv. 2023. PMID: 37333118 Free PMC article. Updated. Preprint.
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications.
Lee JD, Nguyen A, Jin ZR, Moghadasi A, Gibbs CE, Wait SJ, Evitts KM, Asencio A, Bremner SB, Zuniga S, Chavan V, Williams A, Smith N, Regnier M, Young JE, Mack D, Nance E, Boyle PM, Berndt A. Lee JD, et al. bioRxiv [Preprint]. 2024 Feb 8:2024.02.06.579232. doi: 10.1101/2024.02.06.579232. bioRxiv. 2024. PMID: 38370715 Free PMC article. Preprint.
Ultra-fast genetically encoded sensor for precise real-time monitoring of physiological and pathophysiological peroxide dynamics.
Berndt A, Lee J, Won W, Kimball K, Neiswanger C, Schattauer S, Wang Y, Yeboah F, Ruiz M, Evitts K, Rappleye M, Bremner S, Chun C, Smith N, Mack D, Young J, Lee CJ, Chavkin C. Berndt A, et al. Res Sq [Preprint]. 2024 Mar 25:rs.3.rs-4048855. doi: 10.21203/rs.3.rs-4048855/v1. Res Sq. 2024. PMID: 38585715 Free PMC article. Preprint.
Far-red and sensitive sensor for monitoring real time H2O2 dynamics with subcellular resolution and in multi-parametric imaging applications.
Berndt A, Lee J, Nguyen A, Jin Z, Moghadasi A, Gibbs C, Wait S, Evitts K, Asencio A, Bremner S, Zuniga S, Chavan V, Williams A, Smith A, Moussavi-Harami F, Regnier M, Young J, Mack D, Nance E, Boyle P. Berndt A, et al. Res Sq [Preprint]. 2024 Apr 17:rs.3.rs-3974015. doi: 10.21203/rs.3.rs-3974015/v1. Res Sq. 2024. PMID: 38699332 Free PMC article. Preprint.
Human Induced Pluripotent Stem Cell-Derived TDP-43 Mutant Neurons Exhibit Consistent Functional Phenotypes Across Multiple Gene Edited Lines Despite Transcriptomic and Splicing Discrepancies.
Smith AST, Chun C, Hesson J, Mathieu J, Valdmanis PN, Mack DL, Choi BO, Kim DH, Bothwell M. Smith AST, et al. Among authors: mack dl. Front Cell Dev Biol. 2021 Sep 29;9:728707. doi: 10.3389/fcell.2021.728707. eCollection 2021. Front Cell Dev Biol. 2021. PMID: 34660586 Free PMC article.
62 results