Macintyre AN - Search Results

1

The glucose transporter Glut1 is selectively essential for CD4 T cell activation and effector function.

Macintyre AN, Gerriets VA, Nichols AG, Michalek RD, Rudolph MC, Deoliveira D, Anderson SM, Abel ED, Chen BJ, Hale LP, Rathmell JC. Macintyre AN, et al. Cell Metab. 2014 Jul 1;20(1):61-72. doi: 10.1016/j.cmet.2014.05.004. Epub 2014 Jun 12. Cell Metab. 2014. PMID: 24930970 Free PMC article.

2

Autophagy is essential to suppress cell stress and to allow BCR-Abl-mediated leukemogenesis.

Altman BJ, Jacobs SR, Mason EF, Michalek RD, MacIntyre AN, Coloff JL, Ilkayeva O, Jia W, He YW, Rathmell JC. Altman BJ, et al. Among authors: macintyre an. Oncogene. 2011 Apr 21;30(16):1855-67. doi: 10.1038/onc.2010.561. Epub 2010 Dec 13. Oncogene. 2011. PMID: 21151168 Free PMC article.

3

Cutting edge: distinct glycolytic and lipid oxidative metabolic programs are essential for effector and regulatory CD4+ T cell subsets.

Michalek RD, Gerriets VA, Jacobs SR, Macintyre AN, MacIver NJ, Mason EF, Sullivan SA, Nichols AG, Rathmell JC. Michalek RD, et al. Among authors: macintyre an. J Immunol. 2011 Mar 15;186(6):3299-303. doi: 10.4049/jimmunol.1003613. Epub 2011 Feb 11. J Immunol. 2011. PMID: 21317389 Free PMC article.

4

Akt-dependent glucose metabolism promotes Mcl-1 synthesis to maintain cell survival and resistance to Bcl-2 inhibition.

Coloff JL, Macintyre AN, Nichols AG, Liu T, Gallo CA, Plas DR, Rathmell JC. Coloff JL, et al. Among authors: macintyre an. Cancer Res. 2011 Aug 1;71(15):5204-13. doi: 10.1158/0008-5472.CAN-10-4531. Epub 2011 Jun 13. Cancer Res. 2011. PMID: 21670080 Free PMC article.

5

PKM2 and the tricky balance of growth and energy in cancer.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Mol Cell. 2011 Jun 24;42(6):713-4. doi: 10.1016/j.molcel.2011.06.003. Mol Cell. 2011. PMID: 21700216 Free PMC article.

6

Engineering a BCR-ABL-activated caspase for the selective elimination of leukemic cells.

Kurokawa M, Ito T, Yang CS, Zhao C, Macintyre AN, Rizzieri DA, Rathmell JC, Deininger MW, Reya T, Kornbluth S. Kurokawa M, et al. Among authors: macintyre an. Proc Natl Acad Sci U S A. 2013 Feb 5;110(6):2300-5. doi: 10.1073/pnas.1206551110. Epub 2013 Jan 16. Proc Natl Acad Sci U S A. 2013. PMID: 23324740 Free PMC article.

7

Activated lymphocytes as a metabolic model for carcinogenesis.

Macintyre AN, Rathmell JC. Macintyre AN, et al. Cancer Metab. 2013 Jan 23;1(1):5. doi: 10.1186/2049-3002-1-5. Cancer Metab. 2013. PMID: 24280044 Free PMC article.

8

Metabolic reprogramming towards aerobic glycolysis correlates with greater proliferative ability and resistance to metabolic inhibition in CD8 versus CD4 T cells.

Cao Y, Rathmell JC, Macintyre AN. Cao Y, et al. Among authors: macintyre an. PLoS One. 2014 Aug 4;9(8):e104104. doi: 10.1371/journal.pone.0104104. eCollection 2014. PLoS One. 2014. PMID: 25090630 Free PMC article.

9

Glucose transporter 1-mediated glucose uptake is limiting for B-cell acute lymphoblastic leukemia anabolic metabolism and resistance to apoptosis.

Liu T, Kishton RJ, Macintyre AN, Gerriets VA, Xiang H, Liu X, Abel ED, Rizzieri D, Locasale JW, Rathmell JC. Liu T, et al. Among authors: macintyre an. Cell Death Dis. 2014 Oct 16;5(10):e1470. doi: 10.1038/cddis.2014.431. Cell Death Dis. 2014. PMID: 25321477 Free PMC article.

10

Metabolic programming and PDHK1 control CD4+ T cell subsets and inflammation.

Gerriets VA, Kishton RJ, Nichols AG, Macintyre AN, Inoue M, Ilkayeva O, Winter PS, Liu X, Priyadharshini B, Slawinska ME, Haeberli L, Huck C, Turka LA, Wood KC, Hale LP, Smith PA, Schneider MA, MacIver NJ, Locasale JW, Newgard CB, Shinohara ML, Rathmell JC. Gerriets VA, et al. Among authors: macintyre an. J Clin Invest. 2015 Jan;125(1):194-207. doi: 10.1172/JCI76012. Epub 2014 Dec 1. J Clin Invest. 2015. PMID: 25437876 Free PMC article.

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