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Glucocorticoid receptor-dependent therapeutic efficacy of tauroursodeoxycholic acid in preclinical models of spinocerebellar ataxia type 3.
Duarte-Silva S, Da Silva JD, Monteiro-Fernandes D, Costa MD, Neves-Carvalho A, Raposo M, Soares-Cunha C, Correia JS, Nogueira-Goncalves G, Fernandes HS, Oliveira S, Ferreira-Fernandes AR, Rodrigues F, Pereira-Sousa J, Vilasboas-Campos D, Guerreiro S, Campos J, Meireles-Costa L, Rodrigues CMP, Cabantous S, Sousa SF, Lima M, Teixeira-Castro A, Maciel P. Duarte-Silva S, et al. Among authors: maciel p. J Clin Invest. 2024 Mar 1;134(5):e162246. doi: 10.1172/JCI162246. J Clin Invest. 2024. PMID: 38227368 Free PMC article.
Drug repurposing of dopaminergic drugs to inhibit ataxin-3 aggregation.
Figueiredo F, Sárkány Z, Silva A, Vilasboas-Campos D, Maciel P, Teixeira-Castro A, Martins PM, Macedo-Ribeiro S. Figueiredo F, et al. Among authors: maciel p. Biomed Pharmacother. 2023 Sep;165:115258. doi: 10.1016/j.biopha.2023.115258. Epub 2023 Aug 5. Biomed Pharmacother. 2023. PMID: 37549460 Free article.
In vitro and in vivo evaluation of novel chromeno[2,3-d]pyrimidinones as therapeutic agents for triple negative breast cancer.
Carvalho L, de Lima FP, Cerqueira M, Silva A, Pontes O, Oliveira-Pinto S, Guerreiro S, Costa MD, Granja S, Maciel P, Longatto-Filho A, Baltazar F, Proença F, Costa M. Carvalho L, et al. Among authors: maciel p. RSC Med Chem. 2024 Mar 19;15(4):1362-1380. doi: 10.1039/d3md00682d. eCollection 2024 Apr 24. RSC Med Chem. 2024. PMID: 38665823
Global seasonal prediction of fire danger.
Di Giuseppe F, Vitolo C, Barnard C, Libertá G, Maciel P, San-Miguel-Ayanz J, Villaume S, Wetterhall F. Di Giuseppe F, et al. Among authors: maciel p. Sci Data. 2024 Jan 25;11(1):128. doi: 10.1038/s41597-024-02948-3. Sci Data. 2024. PMID: 38272947 Free PMC article.
Correction: The Role of the Mammalian DNA End-processing Enzyme Polynucleotide Kinase 3'-Phosphatase in Spinocerebellar Ataxia Type 3 Pathogenesis.
Chatterjee A, Saha S, Chakraborty A, Silva-Fernandes A, Mandal SM, Neves-Carvalho A, Liu Y, Pandita RK, Hegde ML, Hegde PM, Boldogh I, Ashizawa T, Koeppen AH, Pandita TK, Maciel P, Sarkar PS, Hazra TK. Chatterjee A, et al. Among authors: maciel p. PLoS Genet. 2024 Jan 18;20(1):e1011124. doi: 10.1371/journal.pgen.1011124. eCollection 2024 Jan. PLoS Genet. 2024. PMID: 38236804 Free PMC article.
Genetic Ablation of Inositol 1,4,5-Trisphosphate Receptor Type 2 (IP3R2) Fails to Modify Disease Progression in a Mouse Model of Spinocerebellar Ataxia Type 3.
Cunha-Garcia D, Monteiro-Fernandes D, Correia JS, Neves-Carvalho A, Vilaça-Ferreira AC, Guerra-Gomes S, Viana JF, Oliveira JF, Teixeira-Castro A, Maciel P, Duarte-Silva S. Cunha-Garcia D, et al. Among authors: maciel p. Int J Mol Sci. 2023 Jun 25;24(13):10606. doi: 10.3390/ijms241310606. Int J Mol Sci. 2023. PMID: 37445783 Free PMC article.
225 results