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Tumor-derived semaphorin 4A improves PD-1-blocking antibody efficacy by enhancing CD8+ T cell cytotoxicity and proliferation.
Naito Y, Koyama S, Masuhiro K, Hirai T, Uenami T, Inoue T, Osa A, Machiyama H, Watanabe G, Sax N, Villa J, Kinugasa-Katayama Y, Nojima S, Yaga M, Hosono Y, Okuzaki D, Satoh S, Tsuda T, Nakanishi Y, Suga Y, Morita T, Fukushima K, Nishide M, Shiroyama T, Miyake K, Iwahori K, Hirata H, Nagatomo I, Yano Y, Tamiya M, Kumagai T, Takemoto N, Inohara H, Yamasaki S, Yamashita K, Aoshi T, Akbay EA, Hosen N, Shintani Y, Takamatsu H, Mori M, Takeda Y, Kumanogoh A. Naito Y, et al. Among authors: machiyama h. Sci Adv. 2023 May 19;9(20):eade0718. doi: 10.1126/sciadv.ade0718. Epub 2023 May 19. Sci Adv. 2023. PMID: 37205755 Free PMC article.
Clinical implications of monitoring nivolumab immunokinetics in non-small cell lung cancer patients.
Osa A, Uenami T, Koyama S, Fujimoto K, Okuzaki D, Takimoto T, Hirata H, Yano Y, Yokota S, Kinehara Y, Naito Y, Otsuka T, Kanazu M, Kuroyama M, Hamaguchi M, Koba T, Futami Y, Ishijima M, Suga Y, Akazawa Y, Machiyama H, Iwahori K, Takamatsu H, Nagatomo I, Takeda Y, Kida H, Akbay EA, Hammerman PS, Wong KK, Dranoff G, Mori M, Kijima T, Kumanogoh A. Osa A, et al. Among authors: machiyama h. JCI Insight. 2018 Oct 4;3(19):e59125. doi: 10.1172/jci.insight.59125. JCI Insight. 2018. PMID: 30282824 Free PMC article.
Lipid nanoparticles of Type-A CpG D35 suppress tumor growth by changing tumor immune-microenvironment and activate CD8 T cells in mice.
Munakata L, Tanimoto Y, Osa A, Meng J, Haseda Y, Naito Y, Machiyama H, Kumanogoh A, Omata D, Maruyama K, Yoshioka Y, Okada Y, Koyama S, Suzuki R, Aoshi T. Munakata L, et al. Among authors: machiyama h. J Control Release. 2019 Nov 10;313:106-119. doi: 10.1016/j.jconrel.2019.09.011. Epub 2019 Oct 16. J Control Release. 2019. PMID: 31629036 Free article.
Evaluation of therapeutic PD-1 antibodies by an advanced single-molecule imaging system detecting human PD-1 microclusters.
Nishi W, Wakamatsu E, Machiyama H, Matsushima R, Saito K, Yoshida Y, Nishikawa T, Takehara T, Toyota H, Furuhata M, Nishijima H, Takeuchi A, Azuma M, Suzuki M, Yokosuka T. Nishi W, et al. Among authors: machiyama h. Nat Commun. 2023 Jun 6;14(1):3157. doi: 10.1038/s41467-023-38512-7. Nat Commun. 2023. PMID: 37280233 Free PMC article.
28 results