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Type I IFNs promote cancer cell stemness by triggering the epigenetic regulator KDM1B.
Musella M, Guarracino A, Manduca N, Galassi C, Ruggiero E, Potenza A, Maccafeo E, Manic G, Mattiello L, Soliman Abdel Rehim S, Signore M, Pietrosanto M, Helmer-Citterich M, Pallocca M, Fanciulli M, Bruno T, De Nicola F, Corleone G, Di Benedetto A, Ercolani C, Pescarmona E, Pizzuti L, Guidi F, Sperati F, Vitale S, Macchia D, Spada M, Schiavoni G, Mattei F, De Ninno A, Businaro L, Lucarini V, Bracci L, Aricò E, Ziccheddu G, Facchiano F, Rossi S, Sanchez M, Boe A, Biffoni M, De Maria R, Vitale I, Sistigu A. Musella M, et al. Among authors: macchia d. Nat Immunol. 2022 Sep;23(9):1379-1392. doi: 10.1038/s41590-022-01290-3. Epub 2022 Aug 24. Nat Immunol. 2022. PMID: 36002648 Free PMC article.
IFN-α potentiates the direct and immune-mediated antitumor effects of epigenetic drugs on both metastatic and stem cells of colorectal cancer.
Buoncervello M, Romagnoli G, Buccarelli M, Fragale A, Toschi E, Parlato S, Lucchetti D, Macchia D, Spada M, Canini I, Sanchez M, Falchi M, Musella M, Biffoni M, Belardelli F, Capone I, Sgambato A, Vitiani LR, Gabriele L. Buoncervello M, et al. Among authors: macchia d. Oncotarget. 2016 May 3;7(18):26361-73. doi: 10.18632/oncotarget.8379. Oncotarget. 2016. PMID: 27028869 Free PMC article.
Disruption of IFN-I Signaling Promotes HER2/Neu Tumor Progression and Breast Cancer Stem Cells.
Castiello L, Sestili P, Schiavoni G, Dattilo R, Monque DM, Ciaffoni F, Iezzi M, Lamolinara A, Sistigu A, Moschella F, Pacca AM, Macchia D, Ferrantini M, Zeuner A, Biffoni M, Proietti E, Belardelli F, Aricò E. Castiello L, et al. Among authors: macchia d. Cancer Immunol Res. 2018 Jun;6(6):658-670. doi: 10.1158/2326-6066.CIR-17-0675. Epub 2018 Apr 5. Cancer Immunol Res. 2018. PMID: 29622580
Combining Type I Interferons and 5-Aza-2'-Deoxycitidine to Improve Anti-Tumor Response against Melanoma.
Lucarini V, Buccione C, Ziccheddu G, Peschiaroli F, Sestili P, Puglisi R, Mattia G, Zanetti C, Parolini I, Bracci L, Macchia I, Rossi A, D'Urso MT, Macchia D, Spada M, De Ninno A, Gerardino A, Mozetic P, Trombetta M, Rainer A, Businaro L, Schiavoni G, Mattei F. Lucarini V, et al. Among authors: d urso mt, macchia d, macchia i. J Invest Dermatol. 2017 Jan;137(1):159-169. doi: 10.1016/j.jid.2016.08.024. Epub 2016 Sep 10. J Invest Dermatol. 2017. PMID: 27623509 Free article.
IL-33 restricts tumor growth and inhibits pulmonary metastasis in melanoma-bearing mice through eosinophils.
Lucarini V, Ziccheddu G, Macchia I, La Sorsa V, Peschiaroli F, Buccione C, Sistigu A, Sanchez M, Andreone S, D'Urso MT, Spada M, Macchia D, Afferni C, Mattei F, Schiavoni G. Lucarini V, et al. Among authors: d urso mt, macchia d, macchia i. Oncoimmunology. 2017 Apr 20;6(6):e1317420. doi: 10.1080/2162402X.2017.1317420. eCollection 2017. Oncoimmunology. 2017. PMID: 28680750 Free PMC article.
Anticancer Effects of Sublingual Type I IFN in Combination with Chemotherapy in Implantable and Spontaneous Tumor Models.
Ciccolella M, Andreone S, Mancini J, Sestili P, Negri D, Pacca AM, D'Urso MT, Macchia D, Canese R, Pang K, SaiYing Ko T, Decadt Y, Schiavoni G, Mattei F, Belardelli F, Aricò E, Bracci L. Ciccolella M, et al. Among authors: d urso mt, macchia d. Cells. 2021 Apr 8;10(4):845. doi: 10.3390/cells10040845. Cells. 2021. PMID: 33917958 Free PMC article.
Inflammatory cytokines associated with cancer growth induce mitochondria and cytoskeleton alterations in cardiomyocytes.
Buoncervello M, Maccari S, Ascione B, Gambardella L, Marconi M, Spada M, Macchia D, Stati T, Patrizio M, Malorni W, Matarrese P, Marano G, Gabriele L. Buoncervello M, et al. Among authors: macchia d. J Cell Physiol. 2019 Nov;234(11):20453-20468. doi: 10.1002/jcp.28647. Epub 2019 Apr 14. J Cell Physiol. 2019. PMID: 30982981 Free PMC article.
In vivo antiaging effects of alkaline water supplementation.
Logozzi M, Mizzoni D, Di Raimo R, Andreotti M, Macchia D, Spada M, Fais S. Logozzi M, et al. Among authors: macchia d. J Enzyme Inhib Med Chem. 2020 Dec;35(1):657-664. doi: 10.1080/14756366.2020.1733547. J Enzyme Inhib Med Chem. 2020. PMID: 32106720 Free PMC article.
111 results