Macauley MS - Search Results

1

Siglec-6 mediates the uptake of extracellular vesicles through a noncanonical glycolipid binding pocket.

Schmidt EN, Lamprinaki D, McCord KA, Joe M, Sojitra M, Waldow A, Nguyen J, Monyror J, Kitova EN, Mozaneh F, Guo XY, Jung J, Enterina JR, Daskhan GC, Han L, Krysler AR, Cromwell CR, Hubbard BP, West LJ, Kulka M, Sipione S, Klassen JS, Derda R, Lowary TL, Mahal LK, Riddell MR, Macauley MS. Schmidt EN, et al. Among authors: macauley ms. Nat Commun. 2023 Apr 22;14(1):2327. doi: 10.1038/s41467-023-38030-6. Nat Commun. 2023. PMID: 37087495 Free PMC article.

2

Elevation of global O-GlcNAc levels in 3T3-L1 adipocytes by selective inhibition of O-GlcNAcase does not induce insulin resistance.

Macauley MS, Bubb AK, Martinez-Fleites C, Davies GJ, Vocadlo DJ. Macauley MS, et al. J Biol Chem. 2008 Dec 12;283(50):34687-95. doi: 10.1074/jbc.M804525200. Epub 2008 Oct 8. J Biol Chem. 2008. PMID: 18842583 Free PMC article.

3

Probing synergy between two catalytic strategies in the glycoside hydrolase O-GlcNAcase using multiple linear free energy relationships.

Greig IR, Macauley MS, Williams IH, Vocadlo DJ. Greig IR, et al. Among authors: macauley ms. J Am Chem Soc. 2009 Sep 23;131(37):13415-22. doi: 10.1021/ja904506u. J Am Chem Soc. 2009. PMID: 19715310

4

Holes in the Glycan Shield of the Native HIV Envelope Are a Target of Trimer-Elicited Neutralizing Antibodies.

McCoy LE, van Gils MJ, Ozorowski G, Messmer T, Briney B, Voss JE, Kulp DW, Macauley MS, Sok D, Pauthner M, Menis S, Cottrell CA, Torres JL, Hsueh J, Schief WR, Wilson IA, Ward AB, Sanders RW, Burton DR. McCoy LE, et al. Among authors: macauley ms. Cell Rep. 2016 Aug 30;16(9):2327-38. doi: 10.1016/j.celrep.2016.07.074. Epub 2016 Aug 18. Cell Rep. 2016. PMID: 27545891 Free PMC article.

5

Elevation of Global O-GlcNAc in rodents using a selective O-GlcNAcase inhibitor does not cause insulin resistance or perturb glucohomeostasis.

Macauley MS, Shan X, Yuzwa SA, Gloster TM, Vocadlo DJ. Macauley MS, et al. Chem Biol. 2010 Sep 24;17(9):949-58. doi: 10.1016/j.chembiol.2010.07.005. Chem Biol. 2010. PMID: 20851344 Free PMC article.

6

Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).

Sinclair DA, Syrzycka M, Macauley MS, Rastgardani T, Komljenovic I, Vocadlo DJ, Brock HW, Honda BM. Sinclair DA, et al. Among authors: macauley ms. Proc Natl Acad Sci U S A. 2009 Aug 11;106(32):13427-32. doi: 10.1073/pnas.0904638106. Epub 2009 Jul 28. Proc Natl Acad Sci U S A. 2009. PMID: 19666537 Free PMC article.

7

O-GlcNAcase catalyzes cleavage of thioglycosides without general acid catalysis.

Macauley MS, Stubbs KA, Vocadlo DJ. Macauley MS, et al. J Am Chem Soc. 2005 Dec 14;127(49):17202-3. doi: 10.1021/ja0567687. J Am Chem Soc. 2005. PMID: 16332065

8

Visualizing the reaction coordinate of an O-GlcNAc hydrolase.

He Y, Macauley MS, Stubbs KA, Vocadlo DJ, Davies GJ. He Y, et al. Among authors: macauley ms. J Am Chem Soc. 2010 Feb 17;132(6):1807-9. doi: 10.1021/ja9086769. J Am Chem Soc. 2010. PMID: 20067256

9

Increasing O-GlcNAc levels: An overview of small-molecule inhibitors of O-GlcNAcase.

Macauley MS, Vocadlo DJ. Macauley MS, et al. Biochim Biophys Acta. 2010 Feb;1800(2):107-21. doi: 10.1016/j.bbagen.2009.07.028. Epub 2009 Aug 4. Biochim Biophys Acta. 2010. PMID: 19664691 Review.

10

Inhibition of O-GlcNAcase using a potent and cell-permeable inhibitor does not induce insulin resistance in 3T3-L1 adipocytes.

Macauley MS, He Y, Gloster TM, Stubbs KA, Davies GJ, Vocadlo DJ. Macauley MS, et al. Chem Biol. 2010 Sep 24;17(9):937-48. doi: 10.1016/j.chembiol.2010.07.006. Chem Biol. 2010. PMID: 20851343 Free PMC article.

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