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Hepatoprotection by the farnesoid X receptor agonist GW4064 in rat models of intra- and extrahepatic cholestasis.
J Clin Invest. 2003 Dec;112(11):1678-87. doi: 10.1172/JCI18945. Epub 2003 Nov 17.
J Clin Invest. 2003.
PMID: 14623915
Free PMC article.
The nuclear receptor PXR is a lithocholic acid sensor that protects against liver toxicity.
Staudinger JL, Goodwin B, Jones SA, Hawkins-Brown D, MacKenzie KI, LaTour A, Liu Y, Klaassen CD, Brown KK, Reinhard J, Willson TM, Koller BH, Kliewer SA.
Staudinger JL, et al. Among authors: mackenzie ki.
Proc Natl Acad Sci U S A. 2001 Mar 13;98(6):3369-74. doi: 10.1073/pnas.051551698.
Proc Natl Acad Sci U S A. 2001.
PMID: 11248085
Free PMC article.
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Predicting QT prolongation in humans during early drug development using hERG inhibition and an anaesthetized guinea-pig model.
Yao X, Anderson DL, Ross SA, Lang DG, Desai BZ, Cooper DC, Wheelan P, McIntyre MS, Bergquist ML, MacKenzie KI, Becherer JD, Hashim MA.
Yao X, et al. Among authors: mackenzie ki.
Br J Pharmacol. 2008 Aug;154(7):1446-56. doi: 10.1038/bjp.2008.267. Epub 2008 Jun 30.
Br J Pharmacol. 2008.
PMID: 18587422
Free PMC article.
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Effects of finasteride, a type 2 5-alpha reductase inhibitor, on fetal development in the rhesus monkey (Macaca mulatta).
Prahalada S, Tarantal AF, Harris GS, Ellsworth KP, Clarke AP, Skiles GL, MacKenzie KI, Kruk LF, Ablin DS, Cukierski MA, Peter CP, vanZwieten MJ, Hendrickx AG.
Prahalada S, et al. Among authors: mackenzie ki.
Teratology. 1997 Feb;55(2):119-31. doi: 10.1002/(SICI)1096-9926(199702)55:2<119::AID-TERA1>3.0.CO;2-Z.
Teratology. 1997.
PMID: 9143092
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Mid-line sinus of the upper lip.
Mackenzie KI.
Mackenzie KI.
J Laryngol Otol. 1970 Feb;84(2):235-8. doi: 10.1017/s002221510007184x.
J Laryngol Otol. 1970.
PMID: 5416439
No abstract available.
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