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Exposure to environmental contaminants and folic acid supplementation intergenerationally impact fetal skeleton development through the paternal lineage in a rat model.
L Charest P, Tessougue E, Lessard M, Herst PM, Navarro P, Kimmins S, Trasler JM, MacFarlane AJ, Benoit-Biancamano MO, Bailey JL, Dalvai M. L Charest P, et al. Among authors: macfarlane aj. Front Toxicol. 2022 Sep 27;4:881622. doi: 10.3389/ftox.2022.881622. eCollection 2022. Front Toxicol. 2022. PMID: 36238601 Free PMC article.
Maternal folic acid supplementation does not counteract the deleterious impact of prenatal exposure to environmental pollutants on lipid homeostasis in male rat descendants.
Navarro P, Dalvai M, Charest PL, Herst PM, Lessard M, Marcotte B, Mitchell PL, Leblanc N, Kimmins S, Trasler J, MacFarlane AJ, Marette A, Bailey JL, Jacques H. Navarro P, et al. Among authors: macfarlane aj. J Dev Orig Health Dis. 2020 Aug;11(4):427-437. doi: 10.1017/S2040174419000497. Epub 2019 Sep 16. J Dev Orig Health Dis. 2020. PMID: 31525320
Prenatal Exposure to Environmentally-Relevant Contaminants Perturbs Male Reproductive Parameters Across Multiple Generations that are Partially Protected by Folic Acid Supplementation.
Lessard M, Herst PM, Charest PL, Navarro P, Joly-Beauparlant C, Droit A, Kimmins S, Trasler J, Benoit-Biancamano MO, MacFarlane AJ, Dalvai M, Bailey JL. Lessard M, et al. Among authors: macfarlane aj. Sci Rep. 2019 Sep 25;9(1):13829. doi: 10.1038/s41598-019-50060-z. Sci Rep. 2019. PMID: 31554827 Free PMC article.
Folic acid supplementation reduces multigenerational sperm miRNA perturbation induced by in utero environmental contaminant exposure.
Herst PM, Dalvai M, Lessard M, Charest PL, Navarro P, Joly-Beauparlant C, Droit A, Trasler JM, Kimmins S, MacFarlane AJ, Benoit-Biancamano MO, Bailey JL. Herst PM, et al. Among authors: macfarlane aj. Environ Epigenet. 2019 Dec 14;5(4):dvz024. doi: 10.1093/eep/dvz024. eCollection 2019 Oct. Environ Epigenet. 2019. PMID: 31853372 Free PMC article.
Knowledge gaps in understanding the metabolic and clinical effects of excess folates/folic acid: a summary, and perspectives, from an NIH workshop.
Maruvada P, Stover PJ, Mason JB, Bailey RL, Davis CD, Field MS, Finnell RH, Garza C, Green R, Gueant JL, Jacques PF, Klurfeld DM, Lamers Y, MacFarlane AJ, Miller JW, Molloy AM, O'Connor DL, Pfeiffer CM, Potischman NA, Rodricks JV, Rosenberg IH, Ross SA, Shane B, Selhub J, Stabler SP, Trasler J, Yamini S, Zappalà G. Maruvada P, et al. Among authors: macfarlane aj. Am J Clin Nutr. 2020 Nov 11;112(5):1390-1403. doi: 10.1093/ajcn/nqaa259. Am J Clin Nutr. 2020. PMID: 33022704 Free PMC article.
174 results