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2021 3
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An integrated gene-to-outcome multimodal database for metabolic dysfunction-associated steatotic liver disease.
Kendall TJ, Jimenez-Ramos M, Turner F, Ramachandran P, Minnier J, McColgan MD, Alam M, Ellis H, Dunbar DR, Kohnen G, Konanahalli P, Oien KA, Bandiera L, Menolascina F, Juncker-Jensen A, Alexander D, Mayor C, Guha IN, Fallowfield JA. Kendall TJ, et al. Nat Med. 2023 Nov;29(11):2939-2953. doi: 10.1038/s41591-023-02602-2. Epub 2023 Oct 30. Nat Med. 2023. PMID: 37903863 Free PMC article.
Immunology of human fibrosis.
Bhattacharya M, Ramachandran P. Bhattacharya M, et al. Nat Immunol. 2023 Sep;24(9):1423-1433. doi: 10.1038/s41590-023-01551-9. Epub 2023 Jul 20. Nat Immunol. 2023. PMID: 37474654 Review.
Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling.
Kotsiliti E, Leone V, Schuehle S, Govaere O, Li H, Wolf MJ, Horvatic H, Bierwirth S, Hundertmark J, Inverso D, Zizmare L, Sarusi-Portuguez A, Gupta R, O'Connor T, Giannou AD, Shiri AM, Schlesinger Y, Beccaria MG, Rennert C, Pfister D, Öllinger R, Gadjalova I, Ramadori P, Rahbari M, Rahbari N, Healy ME, Fernández-Vaquero M, Yahoo N, Janzen J, Singh I, Fan C, Liu X, Rau M, Feuchtenberger M, Schwaneck E, Wallace SJ, Cockell S, Wilson-Kanamori J, Ramachandran P, Kho C, Kendall TJ, Leblond AL, Keppler SJ, Bielecki P, Steiger K, Hofmann M, Rippe K, Zitzelsberger H, Weber A, Malek N, Luedde T, Vucur M, Augustin HG, Flavell R, Parnas O, Rad R, Pabst O, Henderson NC, Huber S, Macpherson A, Knolle P, Claassen M, Geier A, Trautwein C, Unger K, Elinav E, Waisman A, Abdullah Z, Haller D, Tacke F, Anstee QM, Heikenwalder M. Kotsiliti E, et al. J Hepatol. 2023 Aug;79(2):296-313. doi: 10.1016/j.jhep.2023.04.037. Epub 2023 May 22. J Hepatol. 2023. PMID: 37224925 Free PMC article.
Macrophages promote anti-androgen resistance in prostate cancer bone disease.
Li XF, Selli C, Zhou HL, Cao J, Wu S, Ma RY, Lu Y, Zhang CB, Xun B, Lam AD, Pang XC, Fernando A, Zhang Z, Unciti-Broceta A, Carragher NO, Ramachandran P, Henderson NC, Sun LL, Hu HY, Li GB, Sawyers C, Qian BZ. Li XF, et al. J Exp Med. 2023 Apr 3;220(4):e20221007. doi: 10.1084/jem.20221007. Epub 2023 Feb 7. J Exp Med. 2023. PMID: 36749798 Free PMC article.
Human and murine fibroblast single-cell transcriptomics reveals fibroblast clusters are differentially affected by ageing and serum cholesterol.
van Kuijk K, McCracken IR, Tillie RJHA, Asselberghs SEJ, Kheder DA, Muitjens S, Jin H, Taylor RS, Wichers Schreur R, Kuppe C, Dobie R, Ramachandran P, Gijbels MJ, Temmerman L, Kirkwoord PM, Luyten J, Li Y, Noels H, Goossens P, Wilson-Kanamori JR, Schurgers LJ, Shen YH, Mees BME, Biessen EAL, Henderson NC, Kramann R, Baker AH, Sluimer JC. van Kuijk K, et al. Cardiovasc Res. 2023 Jul 4;119(7):1509-1523. doi: 10.1093/cvr/cvad016. Cardiovasc Res. 2023. PMID: 36718802 Free PMC article.
Macrophages as key regulators of liver health and disease.
Papachristoforou E, Ramachandran P. Papachristoforou E, et al. Int Rev Cell Mol Biol. 2022;368:143-212. doi: 10.1016/bs.ircmb.2022.04.006. Epub 2022 May 9. Int Rev Cell Mol Biol. 2022. PMID: 35636927 Review.
Genome-wide analysis identifies gallstone-susceptibility loci including genes regulating gastrointestinal motility.
Fairfield CJ, Drake TM, Pius R, Bretherick AD, Campbell A, Clark DW, Fallowfield JA, Hayward C, Henderson NC, Iakovliev A, Joshi PK, Mills NL, Porteous DJ, Ramachandran P, Semple RK, Shaw CA, Sudlow CLW, Timmers PRHJ, Wilson JF, Wigmore SJ, Spiliopoulou A, Harrison EM. Fairfield CJ, et al. Hepatology. 2022 May;75(5):1081-1094. doi: 10.1002/hep.32199. Epub 2021 Dec 10. Hepatology. 2022. PMID: 34651315
Genome-Wide Association Study of NAFLD Using Electronic Health Records.
Fairfield CJ, Drake TM, Pius R, Bretherick AD, Campbell A, Clark DW, Fallowfield JA, Hayward C, Henderson NC, Joshi PK, Mills NL, Porteous DJ, Ramachandran P, Semple RK, Shaw CA, Sudlow CLM, Timmers PRHJ, Wilson JF, Wigmore SJ, Harrison EM, Spiliopoulou A. Fairfield CJ, et al. Hepatol Commun. 2022 Feb;6(2):297-308. doi: 10.1002/hep4.1805. Epub 2021 Sep 17. Hepatol Commun. 2022. PMID: 34535985 Free PMC article.
Deciphering Mesenchymal Drivers of Human Dupuytren's Disease at Single-Cell Level.
Dobie R, West CC, Henderson BEP, Wilson-Kanamori JR, Markose D, Kitto LJ, Portman JR, Beltran M, Sohrabi S, Akram AR, Ramachandran P, Yong LY, Davidson D, Henderson NC. Dobie R, et al. J Invest Dermatol. 2022 Jan;142(1):114-123.e8. doi: 10.1016/j.jid.2021.05.030. Epub 2021 Jul 16. J Invest Dermatol. 2022. PMID: 34274346 Free article.