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2020 2
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Page 1
A Randomized Controlled Clinical Trial of Nasal Immunization with Live Virulence Attenuated Streptococcus pneumoniae Strains Using Human Infection Challenge.
Hill H, Mitsi E, Nikolaou E, Blizard A, Pojar S, Howard A, Hyder-Wright A, Devin J, Reiné J, Robinson R, Solórzano C, Jochems SP, Kenny-Nyazika T, Ramos-Sevillano E, Weight CM, Myerscough C, McLenaghan D, Morton B, Gibbons E, Farrar M, Randles V, Burhan H, Chen T, Shandling AD, Campo JJ, Heyderman RS, Gordon SB, Brown JS, Collins AM, Ferreira DM. Hill H, et al. Am J Respir Crit Care Med. 2023 Oct 15;208(8):868-878. doi: 10.1164/rccm.202302-0222OC. Am J Respir Crit Care Med. 2023. PMID: 37556679 Clinical Trial.
Innate and adaptive nasal mucosal immune responses following experimental human pneumococcal colonization.
Jochems SP, de Ruiter K, Solórzano C, Voskamp A, Mitsi E, Nikolaou E, Carniel BF, Pojar S, German EL, Reiné J, Soares-Schanoski A, Hill H, Robinson R, Hyder-Wright AD, Weight CM, Durrenberger PF, Heyderman RS, Gordon SB, Smits HH, Urban BC, Rylance J, Collins AM, Wilkie MD, Lazarova L, Leong SC, Yazdanbakhsh M, Ferreira DM. Jochems SP, et al. J Clin Invest. 2022 Jun 1;132(11):e161565. doi: 10.1172/JCI161565. J Clin Invest. 2022. PMID: 35642639 Free PMC article. No abstract available.
Acute bacterial meningitis.
Wall EC, Chan JM, Gil E, Heyderman RS. Wall EC, et al. Curr Opin Neurol. 2021 Jun 1;34(3):386-395. doi: 10.1097/WCO.0000000000000934. Curr Opin Neurol. 2021. PMID: 33767093 Free PMC article. Review.
CSF Levels of Elongation Factor Tu Is Associated With Increased Mortality in Malawian Adults With Streptococcus pneumoniae Meningitis.
Wall EC, Brownridge P, Laing G, Terra VS, Mlozowa V, Denis B, Nyirenda M, Allain T, Ramos-Sevillano E, Carrol E, Collins A, Gordon SB, Lalloo DG, Wren B, Beynon R, Heyderman RS, Brown JS. Wall EC, et al. Front Cell Infect Microbiol. 2020 Dec 11;10:603623. doi: 10.3389/fcimb.2020.603623. eCollection 2020. Front Cell Infect Microbiol. 2020. PMID: 33363056 Free PMC article.
Preclinical Development of Virulence-attenuated Streptococcus pneumoniae Strains Able to Enhance Protective Immunity against Pneumococcal Infection.
Ramos-Sevillano E, Ercoli G, Felgner P, Ramiro de Assis R, Nakajima R, Goldblatt D, Heyderman RS, Gordon SB, Ferreira DM, Brown JS. Ramos-Sevillano E, et al. Am J Respir Crit Care Med. 2021 Apr 15;203(8):1037-1041. doi: 10.1164/rccm.202011-4161LE. Am J Respir Crit Care Med. 2021. PMID: 33332997 Free PMC article. No abstract available.