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Year Number of Results
2018 7
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2020 4
2021 3
2022 5
2023 1
2024 0

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Page 1
Unified classification and risk-stratification in Acute Myeloid Leukemia.
Tazi Y, Arango-Ossa JE, Zhou Y, Bernard E, Thomas I, Gilkes A, Freeman S, Pradat Y, Johnson SJ, Hills R, Dillon R, Levine MF, Leongamornlert D, Butler A, Ganser A, Bullinger L, Döhner K, Ottmann O, Adams R, Döhner H, Campbell PJ, Burnett AK, Dennis M, Russell NH, Devlin SM, Huntly BJP, Papaemmanuil E. Tazi Y, et al. Nat Commun. 2022 Aug 8;13(1):4622. doi: 10.1038/s41467-022-32103-8. Nat Commun. 2022. PMID: 35941135 Free PMC article.
KAT2A complexes ATAC and SAGA play unique roles in cell maintenance and identity in hematopoiesis and leukemia.
Arede L, Foerner E, Wind S, Kulkarni R, Domingues AF, Giotopoulos G, Kleinwaechter S, Mollenhauer-Starkl M, Davison H, Chandru A, Asby R, Samarista R, Gupta S, Forte D, Curti A, Scheer E, Huntly BJP, Tora L, Pina C. Arede L, et al. Blood Adv. 2022 Jan 11;6(1):165-180. doi: 10.1182/bloodadvances.2020002842. Blood Adv. 2022. PMID: 34654054 Free PMC article.
Mutational synergy during leukemia induction remodels chromatin accessibility, histone modifications and three-dimensional DNA topology to alter gene expression.
Yun H, Narayan N, Vohra S, Giotopoulos G, Mupo A, Madrigal P, Sasca D, Lara-Astiaso D, Horton SJ, Agrawal-Singh S, Meduri E, Basheer F, Marando L, Gozdecka M, Dovey OM, Castillo-Venzor A, Wang X, Gallipoli P, Müller-Tidow C, Osborne CS, Vassiliou GS, Huntly BJP. Yun H, et al. Nat Genet. 2021 Oct;53(10):1443-1455. doi: 10.1038/s41588-021-00925-9. Epub 2021 Sep 23. Nat Genet. 2021. PMID: 34556857 Free PMC article.
Sequential inverse dysregulation of the RNA helicases DDX3X and DDX3Y facilitates MYC-driven lymphomagenesis.
Gong C, Krupka JA, Gao J, Grigoropoulos NF, Giotopoulos G, Asby R, Screen M, Usheva Z, Cucco F, Barrans S, Painter D, Zaini NBM, Haupl B, Bornelöv S, Ruiz De Los Mozos I, Meng W, Zhou P, Blain AE, Forde S, Matthews J, Khim Tan MG, Burke GAA, Sze SK, Beer P, Burton C, Campbell P, Rand V, Turner SD, Ule J, Roman E, Tooze R, Oellerich T, Huntly BJ, Turner M, Du MQ, Samarajiwa SA, Hodson DJ. Gong C, et al. Mol Cell. 2021 Oct 7;81(19):4059-4075.e11. doi: 10.1016/j.molcel.2021.07.041. Epub 2021 Aug 25. Mol Cell. 2021. PMID: 34437837 Free article.
27 results