MR/L010593/1/MRC_/Medical Research Council/United Kingdom[Grants and Funding] - Search Results

Year	Number of Results
2014	3
2015	4
2016	2
2017	5
2018	2
2019	5
2020	5
2021	10
2022	3
2023	3
2024	0

1

The Endotoxin Hypothesis of Parkinson's Disease.

Brown GC, Camacho M, Williams-Gray CH. Brown GC, et al. Mov Disord. 2023 Jul;38(7):1143-1155. doi: 10.1002/mds.29432. Epub 2023 May 8. Mov Disord. 2023. PMID: 37157885 Free PMC article. Review.

2

Syk inhibitors protect against microglia-mediated neuronal loss in culture.

Birkle TJY, Brown GC. Birkle TJY, et al. Front Aging Neurosci. 2023 Mar 15;15:1120952. doi: 10.3389/fnagi.2023.1120952. eCollection 2023. Front Aging Neurosci. 2023. PMID: 37009452 Free PMC article.

3

P2Y₆ receptor-dependent microglial phagocytosis of synapses mediates synaptic and memory loss in aging.

Dundee JM, Puigdellívol M, Butler R, Cockram TOJ, Brown GC. Dundee JM, et al. Aging Cell. 2023 Feb;22(2):e13761. doi: 10.1111/acel.13761. Epub 2022 Dec 24. Aging Cell. 2023. PMID: 36565471 Free PMC article.

4

Neu1 Is Released From Activated Microglia, Stimulating Microglial Phagocytosis and Sensitizing Neurons to Glutamate.

Allendorf DH, Brown GC. Allendorf DH, et al. Front Cell Neurosci. 2022 May 26;16:917884. doi: 10.3389/fncel.2022.917884. eCollection 2022. Front Cell Neurosci. 2022. PMID: 35693885 Free PMC article.

5

Does Soluble TREM2 Protect Against Alzheimer's Disease?

Brown GC, St George-Hyslop P. Brown GC, et al. Front Aging Neurosci. 2022 Jan 28;13:834697. doi: 10.3389/fnagi.2021.834697. eCollection 2021. Front Aging Neurosci. 2022. PMID: 35153729 Free PMC article. Review.

6

The microglial P2Y₆ receptor mediates neuronal loss and memory deficits in neurodegeneration.

Puigdellívol M, Milde S, Vilalta A, Cockram TOJ, Allendorf DH, Lee JY, Dundee JM, Pampuščenko K, Borutaite V, Nuthall HN, Brelstaff JH, Spillantini MG, Brown GC. Puigdellívol M, et al. Cell Rep. 2021 Dec 28;37(13):110148. doi: 10.1016/j.celrep.2021.110148. Cell Rep. 2021. PMID: 34965424 Free PMC article.

7

Neuronal Loss after Stroke Due to Microglial Phagocytosis of Stressed Neurons.

Brown GC. Brown GC. Int J Mol Sci. 2021 Dec 14;22(24):13442. doi: 10.3390/ijms222413442. Int J Mol Sci. 2021. PMID: 34948237 Free PMC article. Review.

8

Inflammatory neuronal loss in the substantia nigra induced by systemic lipopolysaccharide is prevented by knockout of the P2Y₆ receptor in mice.

Milde S, van Tartwijk FW, Vilalta A, Hornik TC, Dundee JM, Puigdellívol M, Brown GC. Milde S, et al. J Neuroinflammation. 2021 Oct 11;18(1):225. doi: 10.1186/s12974-021-02280-2. J Neuroinflammation. 2021. PMID: 34635136 Free PMC article.

9

The Phagocytic Code Regulating Phagocytosis of Mammalian Cells.

Cockram TOJ, Dundee JM, Popescu AS, Brown GC. Cockram TOJ, et al. Front Immunol. 2021 Jun 9;12:629979. doi: 10.3389/fimmu.2021.629979. eCollection 2021. Front Immunol. 2021. PMID: 34177884 Free PMC article. Review.

10

Wild-type sTREM2 blocks Aβ aggregation and neurotoxicity, but the Alzheimer's R47H mutant increases Aβ aggregation.

Vilalta A, Zhou Y, Sevalle J, Griffin JK, Satoh K, Allendorf DH, De S, Puigdellívol M, Bruzas A, Burguillos MA, Dodd RB, Chen F, Zhang Y, Flagmeier P, Needham LM, Enomoto M, Qamar S, Henderson J, Walter J, Fraser PE, Klenerman D, Lee SF, St George-Hyslop P, Brown GC. Vilalta A, et al. J Biol Chem. 2021 Jan-Jun;296:100631. doi: 10.1016/j.jbc.2021.100631. Epub 2021 Apr 3. J Biol Chem. 2021. PMID: 33823153 Free PMC article.

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