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Extended post-exposure protection against vaginal SHIV infection with tenofovir alafenamide fumarate/elvitegravir inserts in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Bachman S, Holder A, Dinh C, Lipscomb J, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Doncel GF, Smith JM. Makarova N, et al. Among authors: peet mm. J Infect Dis. 2023 Dec 22:jiad599. doi: 10.1093/infdis/jiad599. Online ahead of print. J Infect Dis. 2023. PMID: 38134382
Single dose topical inserts containing tenofovir alafenamide fumarate and elvitegravir provide pre- and post-exposure protection against vaginal SHIV infection in macaques.
Dobard CW, Peet MM, Nishiura K, Holder A, Dinh C, Mitchell J, Khalil G, Pan Y, Singh ON, McCormick TJ, Agrahari V, Gupta P, Jonnalagadda S, Heneine W, Clark MR, García-Lerma JG, Doncel GF. Dobard CW, et al. Among authors: peet mm. EBioMedicine. 2022 Dec;86:104361. doi: 10.1016/j.ebiom.2022.104361. Epub 2022 Nov 21. EBioMedicine. 2022. PMID: 36423375 Free PMC article.
Pharmacokinetics and efficacy of topical inserts containing tenofovir alafenamide fumarate and elvitegravir administered rectally in macaques.
Makarova N, Singletary T, Peet MM, Mitchell J, Holder A, Dinh C, Agrahari V, Mendoza M, Pan Y, Heneine W, Clark MR, García-Lerma JG, Smith JM, Doncel GF. Makarova N, et al. Among authors: peet mm. EBioMedicine. 2022 Dec;86:104338. doi: 10.1016/j.ebiom.2022.104338. Epub 2022 Nov 5. EBioMedicine. 2022. PMID: 36343572 Free PMC article.
A Subcutaneous Implant of Tenofovir Alafenamide Fumarate Causes Local Inflammation and Tissue Necrosis in Rabbits and Macaques.
Su JT, Simpson SM, Sung S, Tfaily EB, Veazey R, Marzinke M, Qiu J, Watrous D, Widanapathirana L, Pearson E, Peet MM, Karunakaran D, Grasperge B, Dobek G, Cain CM, Hope T, Kiser PF. Su JT, et al. Among authors: peet mm. Antimicrob Agents Chemother. 2020 Feb 21;64(3):e01893-19. doi: 10.1128/AAC.01893-19. Print 2020 Feb 21. Antimicrob Agents Chemother. 2020. PMID: 31871073 Free PMC article.
18 results