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Neurotoxic reactive astrocytes are induced by activated microglia.
Liddelow SA, Guttenplan KA, Clarke LE, Bennett FC, Bohlen CJ, Schirmer L, Bennett ML, Münch AE, Chung WS, Peterson TC, Wilton DK, Frouin A, Napier BA, Panicker N, Kumar M, Buckwalter MS, Rowitch DH, Dawson VL, Dawson TM, Stevens B, Barres BA. Liddelow SA, et al. Among authors: munch ae. Nature. 2017 Jan 26;541(7638):481-487. doi: 10.1038/nature21029. Epub 2017 Jan 18. Nature. 2017. PMID: 28099414 Free PMC article.
Normal aging induces A1-like astrocyte reactivity.
Clarke LE, Liddelow SA, Chakraborty C, Münch AE, Heiman M, Barres BA. Clarke LE, et al. Among authors: munch ae. Proc Natl Acad Sci U S A. 2018 Feb 20;115(8):E1896-E1905. doi: 10.1073/pnas.1800165115. Epub 2018 Feb 7. Proc Natl Acad Sci U S A. 2018. PMID: 29437957 Free PMC article.
Neurotoxic Reactive Astrocytes Drive Neuronal Death after Retinal Injury.
Guttenplan KA, Stafford BK, El-Danaf RN, Adler DI, Münch AE, Weigel MK, Huberman AD, Liddelow SA. Guttenplan KA, et al. Among authors: munch ae. Cell Rep. 2020 Jun 23;31(12):107776. doi: 10.1016/j.celrep.2020.107776. Cell Rep. 2020. PMID: 32579912 Free PMC article.
Neurotoxic reactive astrocytes induce cell death via saturated lipids.
Guttenplan KA, Weigel MK, Prakash P, Wijewardhane PR, Hasel P, Rufen-Blanchette U, Münch AE, Blum JA, Fine J, Neal MC, Bruce KD, Gitler AD, Chopra G, Liddelow SA, Barres BA. Guttenplan KA, et al. Among authors: munch ae. Nature. 2021 Nov;599(7883):102-107. doi: 10.1038/s41586-021-03960-y. Epub 2021 Oct 6. Nature. 2021. PMID: 34616039
Long-read RNA-seq atlas of novel microglia isoforms elucidates disease-associated genetic regulation of splicing.
Humphrey J, Brophy E, Kosoy R, Zeng B, Coccia E, Mattei D, Ravi A, Efthymiou AG, Navarro E, Muller BZ, Snijders GJ, Allan A, Münch A, Kitata RB, Kleopoulos SP, Argyriou S, Shao Z, Francoeur N, Tsai CF, Gritsenko MA, Monroe ME, Paurus VL, Weitz KK, Shi T, Sebra R, Liu T, de Witte LD, Goate AM, Bennett DA, Haroutunian V, Hoffman GE, Fullard JF, Roussos P, Raj T. Humphrey J, et al. medRxiv [Preprint]. 2023 Dec 1:2023.12.01.23299073. doi: 10.1101/2023.12.01.23299073. medRxiv. 2023. PMID: 38076956 Free PMC article. Preprint.
Oligodendrocyte calcium signaling sculpts myelin sheath morphology.
Iyer M, Kantarci H, Ambiel N, Novak SW, Andrade LR, Lam M, Münch AE, Yu X, Khakh BS, Manor U, Zuchero JB. Iyer M, et al. Among authors: munch ae. bioRxiv [Preprint]. 2023 Apr 12:2023.04.11.536299. doi: 10.1101/2023.04.11.536299. bioRxiv. 2023. PMID: 37090556 Free PMC article. Updated. Preprint.
Hyperglycemia- and neuropathy-induced changes in mitochondria within sensory nerves.
Hamid HS, Mervak CM, Münch AE, Robell NJ, Hayes JM, Porzio MT, Singleton JR, Smith AG, Feldman EL, Lentz SI. Hamid HS, et al. Among authors: munch ae. Ann Clin Transl Neurol. 2014 Oct;1(10):799-812. doi: 10.1002/acn3.119. Epub 2014 Oct 1. Ann Clin Transl Neurol. 2014. PMID: 25493271 Free PMC article.