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Page 1
TOFIMS mass spectrometry-based immunopeptidomics refines tumor antigen identification.
Hoenisch Gravel N, Nelde A, Bauer J, Mühlenbruch L, Schroeder SM, Neidert MC, Scheid J, Lemke S, Dubbelaar ML, Wacker M, Dengler A, Klein R, Mauz PS, Löwenheim H, Hauri-Hohl M, Martin R, Hennenlotter J, Stenzl A, Heitmann JS, Salih HR, Rammensee HG, Walz JS. Hoenisch Gravel N, et al. Among authors: muhlenbruch l. Nat Commun. 2023 Nov 17;14(1):7472. doi: 10.1038/s41467-023-42692-7. Nat Commun. 2023. PMID: 37978195 Free PMC article.
A T-cell antigen atlas for meningioma: novel options for immunotherapy.
Medici G, Freudenmann LK, Velz J, Wang SS, Kapolou K, Paramasivam N, Mühlenbruch L, Kowalewski DJ, Vasella F, Bilich T, Frey BM, Dubbelaar ML, Patterson AB, Zeitlberger AM, Silginer M, Roth P, Weiss T, Wirsching HG, Krayenbühl N, Bozinov O, Regli L, Rammensee HG, Rushing EJ, Sahm F, Walz JS, Weller M, Neidert MC. Medici G, et al. Among authors: muhlenbruch l. Acta Neuropathol. 2023 Aug;146(2):173-190. doi: 10.1007/s00401-023-02605-w. Epub 2023 Jun 27. Acta Neuropathol. 2023. PMID: 37368072 Free PMC article.
The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination.
Mühlenbruch L, Abou-Kors T, Dubbelaar ML, Bichmann L, Kohlbacher O, Bens M, Thomas J, Ezić J, Kraus JM, Kestler HA, von Witzleben A, Mytilineos J, Fürst D, Engelhardt D, Doescher J, Greve J, Schuler PJ, Theodoraki MN, Brunner C, Hoffmann TK, Rammensee HG, Walz JS, Laban S. Mühlenbruch L, et al. Br J Cancer. 2023 May;128(9):1777-1787. doi: 10.1038/s41416-023-02197-y. Epub 2023 Feb 23. Br J Cancer. 2023. PMID: 36823366 Free PMC article.
HLA Ligand Atlas: a benign reference of HLA-presented peptides to improve T-cell-based cancer immunotherapy.
Marcu A, Bichmann L, Kuchenbecker L, Kowalewski DJ, Freudenmann LK, Backert L, Mühlenbruch L, Szolek A, Lübke M, Wagner P, Engler T, Matovina S, Wang J, Hauri-Hohl M, Martin R, Kapolou K, Walz JS, Velz J, Moch H, Regli L, Silginer M, Weller M, Löffler MW, Erhard F, Schlosser A, Kohlbacher O, Stevanović S, Rammensee HG, Neidert MC. Marcu A, et al. Among authors: muhlenbruch l. J Immunother Cancer. 2021 Apr;9(4):e002071. doi: 10.1136/jitc-2020-002071. J Immunother Cancer. 2021. PMID: 33858848 Free PMC article.
The Impact of Biomaterial Cell Contact on the Immunopeptidome.
Ghosh M, Hartmann H, Jakobi M, März L, Bichmann L, Freudenmann LK, Mühlenbruch L, Segan S, Rammensee HG, Schneiderhan-Marra N, Shipp C, Stevanović S, Joos TO. Ghosh M, et al. Among authors: muhlenbruch l. Front Bioeng Biotechnol. 2020 Dec 16;8:571294. doi: 10.3389/fbioe.2020.571294. eCollection 2020. Front Bioeng Biotechnol. 2020. PMID: 33392160 Free PMC article.
HLA-DR15 Molecules Jointly Shape an Autoreactive T Cell Repertoire in Multiple Sclerosis.
Wang J, Jelcic I, Mühlenbruch L, Haunerdinger V, Toussaint NC, Zhao Y, Cruciani C, Faigle W, Naghavian R, Foege M, Binder TMC, Eiermann T, Opitz L, Fuentes-Font L, Reynolds R, Kwok WW, Nguyen JT, Lee JH, Lutterotti A, Münz C, Rammensee HG, Hauri-Hohl M, Sospedra M, Stevanovic S, Martin R. Wang J, et al. Among authors: muhlenbruch l. Cell. 2020 Nov 25;183(5):1264-1281.e20. doi: 10.1016/j.cell.2020.09.054. Epub 2020 Oct 21. Cell. 2020. PMID: 33091337 Free PMC article.
A Non-interventional Clinical Trial Assessing Immune Responses After Radiofrequency Ablation of Liver Metastases From Colorectal Cancer.
Löffler MW, Nussbaum B, Jäger G, Jurmeister PS, Budczies J, Pereira PL, Clasen S, Kowalewski DJ, Mühlenbruch L, Königsrainer I, Beckert S, Ladurner R, Wagner S, Bullinger F, Gross TH, Schroeder C, Sipos B, Königsrainer A, Stevanović S, Denkert C, Rammensee HG, Gouttefangeas C, Haen SP. Löffler MW, et al. Among authors: muhlenbruch l. Front Immunol. 2019 Nov 19;10:2526. doi: 10.3389/fimmu.2019.02526. eCollection 2019. Front Immunol. 2019. PMID: 31803175 Free PMC article. Clinical Trial.
Multi-omics discovery of exome-derived neoantigens in hepatocellular carcinoma.
Löffler MW, Mohr C, Bichmann L, Freudenmann LK, Walzer M, Schroeder CM, Trautwein N, Hilke FJ, Zinser RS, Mühlenbruch L, Kowalewski DJ, Schuster H, Sturm M, Matthes J, Riess O, Czemmel S, Nahnsen S, Königsrainer I, Thiel K, Nadalin S, Beckert S, Bösmüller H, Fend F, Velic A, Maček B, Haen SP, Buonaguro L, Kohlbacher O, Stevanović S, Königsrainer A; HEPAVAC Consortium; Rammensee HG. Löffler MW, et al. Among authors: muhlenbruch l. Genome Med. 2019 Apr 30;11(1):28. doi: 10.1186/s13073-019-0636-8. Genome Med. 2019. PMID: 31039795 Free PMC article.