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Early antiretroviral therapy favors post-treatment SIV control associated with the expansion of enhanced memory CD8+ T-cells.
Passaes C, Desjardins D, Chapel A, Monceaux V, Lemaitre J, Mélard A, Perdomo-Celis F, Planchais C, Gourvès M, Dimant N, David A, Dereuddre-Bosquet N, Barrail-Tran A, Gouget H, Guillaume C, Relouzat F, Lambotte O, Guedj J, Müller-Trutwin M, Mouquet H, Rouzioux C, Avettand-Fenoël V, Le Grand R, Sáez-Cirión A. Passaes C, et al. Among authors: melard a. Nat Commun. 2024 Jan 11;15(1):178. doi: 10.1038/s41467-023-44389-3. Nat Commun. 2024. PMID: 38212337 Free PMC article.
In-Depth Characterization of Full-Length Archived Viral Genomes after Nine Years of Posttreatment HIV Control.
Trémeaux P, Lemoine F, Mélard A, Gousset M, Boufassa F, Orr S, Monceaux V, Gascuel O, Lambotte O, Hocqueloux L, Saez-Cirion A, Rouzioux C, Avettand-Fenoel V. Trémeaux P, et al. Among authors: melard a. Microbiol Spectr. 2023 Feb 14;11(1):e0326722. doi: 10.1128/spectrum.03267-22. Epub 2023 Jan 24. Microbiol Spectr. 2023. PMID: 36692300 Free PMC article.
Post-treatment HIV-1 controllers with a long-term virological remission after the interruption of early initiated antiretroviral therapy ANRS VISCONTI Study.
Sáez-Cirión A, Bacchus C, Hocqueloux L, Avettand-Fenoel V, Girault I, Lecuroux C, Potard V, Versmisse P, Melard A, Prazuck T, Descours B, Guergnon J, Viard JP, Boufassa F, Lambotte O, Goujard C, Meyer L, Costagliola D, Venet A, Pancino G, Autran B, Rouzioux C; ANRS VISCONTI Study Group. Sáez-Cirión A, et al. Among authors: melard a. PLoS Pathog. 2013 Mar;9(3):e1003211. doi: 10.1371/journal.ppat.1003211. Epub 2013 Mar 14. PLoS Pathog. 2013. PMID: 23516360 Free PMC article.
Adipose Tissue Is a Neglected Viral Reservoir and an Inflammatory Site during Chronic HIV and SIV Infection.
Damouche A, Lazure T, Avettand-Fènoël V, Huot N, Dejucq-Rainsford N, Satie AP, Mélard A, David L, Gommet C, Ghosn J, Noel N, Pourcher G, Martinez V, Benoist S, Béréziat V, Cosma A, Favier B, Vaslin B, Rouzioux C, Capeau J, Müller-Trutwin M, Dereuddre-Bosquet N, Le Grand R, Lambotte O, Bourgeois C. Damouche A, et al. Among authors: melard a. PLoS Pathog. 2015 Sep 24;11(9):e1005153. doi: 10.1371/journal.ppat.1005153. eCollection 2015 Sep. PLoS Pathog. 2015. PMID: 26402858 Free PMC article.
Restriction of HIV-1 replication in macrophages and CD4+ T cells from HIV controllers.
Sáez-Cirión A, Hamimi C, Bergamaschi A, David A, Versmisse P, Mélard A, Boufassa F, Barré-Sinoussi F, Lambotte O, Rouzioux C, Pancino G; ANRS CO18 Cohort. Sáez-Cirión A, et al. Among authors: melard a. Blood. 2011 Jul 28;118(4):955-64. doi: 10.1182/blood-2010-12-327106. Epub 2011 Jun 3. Blood. 2011. PMID: 21642597 Free PMC article.
Impact of early cART on HIV blood and semen compartments at the time of primary infection.
Chéret A, Durier C, Mélard A, Ploquin M, Heitzmann J, Lécuroux C, Avettand-Fenoël V, David L, Pialoux G, Chennebault JM, Müller-Trutwin M, Goujard C, Rouzioux C, Meyer L; ANRS OPTIPRIM study group. Chéret A, et al. Among authors: melard a. PLoS One. 2017 Jul 14;12(7):e0180191. doi: 10.1371/journal.pone.0180191. eCollection 2017. PLoS One. 2017. PMID: 28708873 Free PMC article. Clinical Trial.
Initiating Antiretroviral Treatment Early in Infancy Has Long-term Benefits on the Human Immunodeficiency Virus Reservoir in Late Childhood and Adolescence.
Avettand-Fenoel V, Lechenadec J, Diallo MS, Fillion M, Melard A, Samri A, Dollfus C, Blanche S, Faye A, Amokrane K, Autran B, Buseyne F, Warszawski J, Frange P; ANRS-EP59-CLEAC Study Group. Avettand-Fenoel V, et al. Among authors: melard a. Clin Infect Dis. 2021 Dec 6;73(11):e4214-e4222. doi: 10.1093/cid/ciaa1931. Clin Infect Dis. 2021. PMID: 34355738
43 results