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Organotypic Hippocampal Slice Cultures from Adult Tauopathy Mice and Theragnostic Evaluation of Nanomaterial Phospho-TAU Antibody-Conjugates.
Kemppainen S, Huber N, Willman RM, Zamora A, Mäkinen P, Martiskainen H, Takalo M, Haapasalo A, Sobrino T, González Gómez MA, Piñeiro Y, Rivas J, Himmelreich U, Hiltunen M. Kemppainen S, et al. Among authors: makinen p. Cells. 2023 May 18;12(10):1422. doi: 10.3390/cells12101422. Cells. 2023. PMID: 37408256 Free PMC article.
MECP2 Increases the Pro-Inflammatory Response of Microglial Cells and Phosphorylation at Serine 423 Regulates Neuronal Gene Expression upon Neuroinflammation.
Wittrahm R, Takalo M, Marttinen M, Kuulasmaa T, Mäkinen P, Kemppainen S, Martiskainen H, Rauramaa T, Pike I, Leinonen V, Natunen T, Haapasalo A, Hiltunen M. Wittrahm R, et al. Among authors: makinen p. Cells. 2021 Apr 9;10(4):860. doi: 10.3390/cells10040860. Cells. 2021. PMID: 33918872 Free PMC article.
High-fat diet increases tau expression in the brain of T2DM and AD mice independently of peripheral metabolic status.
Takalo M, Haapasalo A, Martiskainen H, Kurkinen KM, Koivisto H, Miettinen P, Khandelwal VK, Kemppainen S, Kaminska D, Mäkinen P, Leinonen V, Pihlajamäki J, Soininen H, Laakso M, Tanila H, Hiltunen M. Takalo M, et al. Among authors: makinen p. J Nutr Biochem. 2014 Jun;25(6):634-41. doi: 10.1016/j.jnutbio.2014.02.003. Epub 2014 Mar 12. J Nutr Biochem. 2014. PMID: 24746833
Diabetic phenotype in mouse and humans reduces the number of microglia around β-amyloid plaques.
Natunen T, Martiskainen H, Marttinen M, Gabbouj S, Koivisto H, Kemppainen S, Kaipainen S, Takalo M, Svobodová H, Leppänen L, Kemiläinen B, Ryhänen S, Kuulasmaa T, Rahunen E, Juutinen S, Mäkinen P, Miettinen P, Rauramaa T, Pihlajamäki J, Haapasalo A, Leinonen V, Tanila H, Hiltunen M. Natunen T, et al. Among authors: makinen p. Mol Neurodegener. 2020 Nov 10;15(1):66. doi: 10.1186/s13024-020-00415-2. Mol Neurodegener. 2020. PMID: 33168021 Free PMC article.
DHCR24 exerts neuroprotection upon inflammation-induced neuronal death.
Martiskainen H, Paldanius KMA, Natunen T, Takalo M, Marttinen M, Leskelä S, Huber N, Mäkinen P, Bertling E, Dhungana H, Huuskonen M, Honkakoski P, Hotulainen P, Rilla K, Koistinaho J, Soininen H, Malm T, Haapasalo A, Hiltunen M. Martiskainen H, et al. Among authors: makinen p. J Neuroinflammation. 2017 Nov 7;14(1):215. doi: 10.1186/s12974-017-0991-6. J Neuroinflammation. 2017. PMID: 29115990 Free PMC article.
The Alzheimer's disease-associated protective Plcγ2-P522R variant promotes immune functions.
Takalo M, Wittrahm R, Wefers B, Parhizkar S, Jokivarsi K, Kuulasmaa T, Mäkinen P, Martiskainen H, Wurst W, Xiang X, Marttinen M, Poutiainen P, Haapasalo A, Hiltunen M, Haass C. Takalo M, et al. Among authors: makinen p. Mol Neurodegener. 2020 Sep 11;15(1):52. doi: 10.1186/s13024-020-00402-7. Mol Neurodegener. 2020. PMID: 32917267 Free PMC article.
BV-2 Microglial Cells Overexpressing C9orf72 Hexanucleotide Repeat Expansion Produce DPR Proteins and Show Normal Functionality but No RNA Foci.
Rostalski H, Hietanen T, Leskelä S, Behánová A, Abdollahzadeh A, Wittrahm R, Mäkinen P, Huber N, Hoffmann D, Solje E, Remes AM, Natunen T, Takalo M, Tohka J, Hiltunen M, Haapasalo A. Rostalski H, et al. Among authors: makinen p. Front Neurol. 2020 Oct 6;11:550140. doi: 10.3389/fneur.2020.550140. eCollection 2020. Front Neurol. 2020. PMID: 33123074 Free PMC article.
Intranasal insulin activates Akt2 signaling pathway in the hippocampus of wild-type but not in APP/PS1 Alzheimer model mice.
Gabbouj S, Natunen T, Koivisto H, Jokivarsi K, Takalo M, Marttinen M, Wittrahm R, Kemppainen S, Naderi R, Posado-Fernández A, Ryhänen S, Mäkinen P, Paldanius KMA, Doria G, Poutiainen P, Flores O, Haapasalo A, Tanila H, Hiltunen M. Gabbouj S, et al. Among authors: makinen p. Neurobiol Aging. 2019 Mar;75:98-108. doi: 10.1016/j.neurobiolaging.2018.11.008. Epub 2018 Nov 17. Neurobiol Aging. 2019. PMID: 30554086 Free article.
200 results