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Protective effects of the novel amine-oxidase inhibitor multi-target drug SZV 1287 on streptozotocin-induced beta cell damage and diabetic complications in rats.
Tékus V, Horváth ÁI, Csekő K, Szabadfi K, Kovács-Valasek A, Dányádi B, Deres L, Halmosi R, Sághy É, Varga ZV, Adeghate E, Kőszegi T, Mátyus P, Gábriel R, Ferdinandy P, Pintér E, Helyes Z. Tékus V, et al. Among authors: matyus p. Biomed Pharmacother. 2021 Feb;134:111105. doi: 10.1016/j.biopha.2020.111105. Epub 2020 Dec 15. Biomed Pharmacother. 2021. PMID: 33338750 Free article.
Analgesic and Anti-Inflammatory Effects of the Novel Semicarbazide-Sensitive Amine-Oxidase Inhibitor SzV-1287 in Chronic Arthritis Models of the Mouse.
Horváth Á, Menghis A, Botz B, Borbély É, Kemény Á, Tékus V, Csepregi JZ, Mócsai A, Juhász T, Zákány R, Bogdán D, Mátyus P, Keeble J, Pintér E, Helyes Z. Horváth Á, et al. Among authors: matyus p. Sci Rep. 2017 Jan 9;7:39863. doi: 10.1038/srep39863. Sci Rep. 2017. PMID: 28067251 Free PMC article.
Analgesic effects of the novel semicarbazide-sensitive amine oxidase inhibitor SZV 1287 in mouse pain models with neuropathic mechanisms: Involvement of transient receptor potential vanilloid 1 and ankyrin 1 receptors.
Horváth Á, Tékus V, Bencze N, Szentes N, Scheich B, Bölcskei K, Szőke É, Mócsai A, Tóth-Sarudy É, Mátyus P, Pintér E, Helyes Z. Horváth Á, et al. Among authors: matyus p. Pharmacol Res. 2018 May;131:231-243. doi: 10.1016/j.phrs.2018.02.006. Epub 2018 Feb 10. Pharmacol Res. 2018. PMID: 29438782
Proof-of-Concept for the Analgesic Effect and Thermoregulatory Safety of Orally Administered Multi-Target Compound SZV 1287 in Mice: A Novel Drug Candidate for Neuropathic Pain.
Horváth ÁI, Szentes N, Tékus V, Payrits M, Szőke É, Oláh E, Garami A, Fliszár-Nyúl E, Poór M, Sár C, Kálai T, Pál S, Percze K, Scholz ÉN, Mészáros T, Tóth B, Mátyus P, Helyes Z. Horváth ÁI, et al. Among authors: matyus p. Biomedicines. 2021 Jun 29;9(7):749. doi: 10.3390/biomedicines9070749. Biomedicines. 2021. PMID: 34209525 Free PMC article.
103 results