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Long-term expanding human airway organoids for disease modeling.
Sachs N, Papaspyropoulos A, Zomer-van Ommen DD, Heo I, Böttinger L, Klay D, Weeber F, Huelsz-Prince G, Iakobachvili N, Amatngalim GD, de Ligt J, van Hoeck A, Proost N, Viveen MC, Lyubimova A, Teeven L, Derakhshan S, Korving J, Begthel H, Dekkers JF, Kumawat K, Ramos E, van Oosterhout MF, Offerhaus GJ, Wiener DJ, Olimpio EP, Dijkstra KK, Smit EF, van der Linden M, Jaksani S, van de Ven M, Jonkers J, Rios AC, Voest EE, van Moorsel CH, van der Ent CK, Cuppen E, van Oudenaarden A, Coenjaerts FE, Meyaard L, Bont LJ, Peters PJ, Tans SJ, van Zon JS, Boj SF, Vries RG, Beekman JM, Clevers H. Sachs N, et al. Among authors: lyubimova a. EMBO J. 2019 Feb 15;38(4):e100300. doi: 10.15252/embj.2018100300. Epub 2019 Jan 14. EMBO J. 2019. PMID: 30643021 Free PMC article.
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.
van Es JH, Sato T, van de Wetering M, Lyubimova A, Yee Nee AN, Gregorieff A, Sasaki N, Zeinstra L, van den Born M, Korving J, Martens ACM, Barker N, van Oudenaarden A, Clevers H. van Es JH, et al. Among authors: lyubimova a. Nat Cell Biol. 2012 Oct;14(10):1099-1104. doi: 10.1038/ncb2581. Epub 2012 Sep 23. Nat Cell Biol. 2012. PMID: 23000963 Free PMC article.
De Novo Prediction of Stem Cell Identity using Single-Cell Transcriptome Data.
Grün D, Muraro MJ, Boisset JC, Wiebrands K, Lyubimova A, Dharmadhikari G, van den Born M, van Es J, Jansen E, Clevers H, de Koning EJP, van Oudenaarden A. Grün D, et al. Among authors: lyubimova a. Cell Stem Cell. 2016 Aug 4;19(2):266-277. doi: 10.1016/j.stem.2016.05.010. Epub 2016 Jun 23. Cell Stem Cell. 2016. PMID: 27345837 Free PMC article.
Reg4+ deep crypt secretory cells function as epithelial niche for Lgr5+ stem cells in colon.
Sasaki N, Sachs N, Wiebrands K, Ellenbroek SI, Fumagalli A, Lyubimova A, Begthel H, van den Born M, van Es JH, Karthaus WR, Li VS, López-Iglesias C, Peters PJ, van Rheenen J, van Oudenaarden A, Clevers H. Sasaki N, et al. Among authors: lyubimova a. Proc Natl Acad Sci U S A. 2016 Sep 13;113(37):E5399-407. doi: 10.1073/pnas.1607327113. Epub 2016 Aug 29. Proc Natl Acad Sci U S A. 2016. PMID: 27573849 Free PMC article.
Mapping the physical network of cellular interactions.
Boisset JC, Vivié J, Grün D, Muraro MJ, Lyubimova A, van Oudenaarden A. Boisset JC, et al. Among authors: lyubimova a. Nat Methods. 2018 Jul;15(7):547-553. doi: 10.1038/s41592-018-0009-z. Epub 2018 May 21. Nat Methods. 2018. PMID: 29786092
Cell Type Purification by Single-Cell Transcriptome-Trained Sorting.
Baron CS, Barve A, Muraro MJ, van der Linden R, Dharmadhikari G, Lyubimova A, de Koning EJP, van Oudenaarden A. Baron CS, et al. Among authors: lyubimova a. Cell. 2019 Oct 3;179(2):527-542.e19. doi: 10.1016/j.cell.2019.08.006. Cell. 2019. PMID: 31585086 Free PMC article.
32 results