Lynaugh H - Search Results

1

Affinity Maturation Enhances Antibody Specificity but Compromises Conformational Stability.

Shehata L, Maurer DP, Wec AZ, Lilov A, Champney E, Sun T, Archambault K, Burnina I, Lynaugh H, Zhi X, Xu Y, Walker LM. Shehata L, et al. Among authors: lynaugh h. Cell Rep. 2019 Sep 24;28(13):3300-3308.e4. doi: 10.1016/j.celrep.2019.08.056. Cell Rep. 2019. PMID: 31553901 Free article.

2

Understanding ForteBio's Sensors for High-Throughput Kinetic and Epitope Screening for Purified Antibodies and Yeast Culture Supernatant.

Yu Y, Mitchell S, Lynaugh H, Brown M, Nobrega RP, Zhi X, Sun T, Caffry I, Cao Y, Yang R, Burnina I, Xu Y, Estep P. Yu Y, et al. Among authors: lynaugh h. J Biomol Screen. 2016 Jan;21(1):88-95. doi: 10.1177/1087057115609564. Epub 2015 Oct 6. J Biomol Screen. 2016. PMID: 26442912 Free PMC article.

3

Target-independent variable region mediated effects on antibody clearance can be FcRn independent.

Kelly RL, Yu Y, Sun T, Caffry I, Lynaugh H, Brown M, Jain T, Xu Y, Wittrup KD. Kelly RL, et al. Among authors: lynaugh h. MAbs. 2016 Oct;8(7):1269-1275. doi: 10.1080/19420862.2016.1208330. Epub 2016 Sep 9. MAbs. 2016. PMID: 27610650 Free PMC article.

4

Rapid assessment of oxidation via middle-down LCMS correlates with methionine side-chain solvent-accessible surface area for 121 clinical stage monoclonal antibodies.

Yang R, Jain T, Lynaugh H, Nobrega RP, Lu X, Boland T, Burnina I, Sun T, Caffry I, Brown M, Zhi X, Lilov A, Xu Y. Yang R, et al. Among authors: lynaugh h. MAbs. 2017 May/Jun;9(4):646-653. doi: 10.1080/19420862.2017.1290753. Epub 2017 Feb 14. MAbs. 2017. PMID: 28281887 Free PMC article.

5

Database-Centric Method for Automated High-Throughput Deconvolution and Analysis of Kinetic Antibody Screening Data.

Nobrega RP, Brown M, Williams C, Sumner C, Estep P, Caffry I, Yu Y, Lynaugh H, Burnina I, Lilov A, Desroches J, Bukowski J, Sun T, Belk JP, Johnson K, Xu Y. Nobrega RP, et al. Among authors: lynaugh h. SLAS Technol. 2017 Oct;22(5):547-556. doi: 10.1177/2472630317705611. Epub 2017 Apr 21. SLAS Technol. 2017. PMID: 28430560

6

Assessing the binding properties of the anti-PD-1 antibody landscape using label-free biosensors.

Brown ME, Bedinger D, Lilov A, Rathanaswami P, Vásquez M, Durand S, Wallace-Moyer I, Zhong L, Nett JH, Burnina I, Caffry I, Lynaugh H, Sinclair M, Sun T, Bukowski J, Xu Y, Abdiche YN. Brown ME, et al. Among authors: lynaugh h. PLoS One. 2020 Mar 5;15(3):e0229206. doi: 10.1371/journal.pone.0229206. eCollection 2020. PLoS One. 2020. PMID: 32134960 Free PMC article.

7

A cost-effective plate-based sample preparation for antibody N-glycan analysis.

Burnina I, Hoyt E, Lynaugh H, Li H, Gong B. Burnina I, et al. Among authors: lynaugh h. J Chromatogr A. 2013 Sep 13;1307:201-6. doi: 10.1016/j.chroma.2013.07.104. Epub 2013 Aug 2. J Chromatogr A. 2013. PMID: 23932029

8

Biophysical properties of the clinical-stage antibody landscape.

Jain T, Sun T, Durand S, Hall A, Houston NR, Nett JH, Sharkey B, Bobrowicz B, Caffry I, Yu Y, Cao Y, Lynaugh H, Brown M, Baruah H, Gray LT, Krauland EM, Xu Y, Vásquez M, Wittrup KD. Jain T, et al. Among authors: lynaugh h. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):944-949. doi: 10.1073/pnas.1616408114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096333 Free PMC article.

9

An alternative assay to hydrophobic interaction chromatography for high-throughput characterization of monoclonal antibodies.

Estep P, Caffry I, Yu Y, Sun T, Cao Y, Lynaugh H, Jain T, Vásquez M, Tessier PM, Xu Y. Estep P, et al. Among authors: lynaugh h. MAbs. 2015;7(3):553-61. doi: 10.1080/19420862.2015.1016694. MAbs. 2015. PMID: 25790175 Free PMC article.

10

High-throughput screening and selection of yeast cell lines expressing monoclonal antibodies.

Barnard GC, Kull AR, Sharkey NS, Shaikh SS, Rittenhour AM, Burnina I, Jiang Y, Li F, Lynaugh H, Mitchell T, Nett JH, Nylen A, Potgieter TI, Prinz B, Rios SE, Zha D, Sethuraman N, Stadheim TA, Bobrowicz P. Barnard GC, et al. Among authors: lynaugh h. J Ind Microbiol Biotechnol. 2010 Sep;37(9):961-71. doi: 10.1007/s10295-010-0746-1. Epub 2010 Aug 15. J Ind Microbiol Biotechnol. 2010. PMID: 20711797

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