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A randomized controlled trial showing safety and efficacy of a whole sporozoite vaccine against endemic malaria.
Sirima SB, Ouédraogo A, Tiono AB, Kaboré JM, Bougouma EC, Ouattara MS, Kargougou D, Diarra A, Henry N, Ouédraogo IN, Billingsley PF, Manoj A, Abebe Y, Kc N, Ruben A, Richie TL, James ER, Joshi S, Shrestha B, Strauss K, Lyke KE, Plowe CV, Potter GE, Cox C, Jones W, Sim BKL, Hoffman SL, Laurens MB. Sirima SB, et al. Among authors: lyke ke. Sci Transl Med. 2022 Dec 7;14(674):eabj3776. doi: 10.1126/scitranslmed.abj3776. Epub 2022 Dec 7. Sci Transl Med. 2022. PMID: 36475905 Free PMC article. Clinical Trial.
Serum levels of the proinflammatory cytokines interleukin-1 beta (IL-1beta), IL-6, IL-8, IL-10, tumor necrosis factor alpha, and IL-12(p70) in Malian children with severe Plasmodium falciparum malaria and matched uncomplicated malaria or healthy controls.
Lyke KE, Burges R, Cissoko Y, Sangare L, Dao M, Diarra I, Kone A, Harley R, Plowe CV, Doumbo OK, Sztein MB. Lyke KE, et al. Infect Immun. 2004 Oct;72(10):5630-7. doi: 10.1128/IAI.72.10.5630-5637.2004. Infect Immun. 2004. PMID: 15385460 Free PMC article.
HLA-A2 supertype-restricted cell-mediated immunity by peripheral blood mononuclear cells derived from Malian children with severe or uncomplicated Plasmodium falciparum malaria and healthy controls.
Lyke KE, Burges RB, Cissoko Y, Sangare L, Kone A, Dao M, Diarra I, Fernández-Vina MA, Plowe CV, Doumbo OK, Sztein MB. Lyke KE, et al. Infect Immun. 2005 Sep;73(9):5799-808. doi: 10.1128/IAI.73.9.5799-5808.2005. Infect Immun. 2005. PMID: 16113298 Free PMC article.
107 results