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VARP is recruited on to endosomes by direct interaction with retromer, where together they function in export to the cell surface.
Hesketh GG, Pérez-Dorado I, Jackson LP, Wartosch L, Schäfer IB, Gray SR, McCoy AJ, Zeldin OB, Garman EF, Harbour ME, Evans PR, Seaman MNJ, Luzio JP, Owen DJ. Hesketh GG, et al. Among authors: luzio jp. Dev Cell. 2014 Jun 9;29(5):591-606. doi: 10.1016/j.devcel.2014.04.010. Epub 2014 May 22. Dev Cell. 2014. PMID: 24856514 Free PMC article.
Lysosome fusion in cultured mammalian cells.
Bright NA, Wartosch L, Luzio JP. Bright NA, et al. Among authors: luzio jp. Methods Cell Biol. 2015;126:101-18. doi: 10.1016/bs.mcb.2014.10.029. Epub 2015 Jan 14. Methods Cell Biol. 2015. PMID: 25665443
Mechanism and evolution of the Zn-fingernail required for interaction of VARP with VPS29.
Crawley-Snowdon H, Yang JC, Zaccai NR, Davis LJ, Wartosch L, Herman EK, Bright NA, Swarbrick JS, Collins BM, Jackson LP, Seaman MNJ, Luzio JP, Dacks JB, Neuhaus D, Owen DJ. Crawley-Snowdon H, et al. Among authors: luzio jp. Nat Commun. 2020 Oct 6;11(1):5031. doi: 10.1038/s41467-020-18773-2. Nat Commun. 2020. PMID: 33024112 Free PMC article.
The delivery of endocytosed cargo to lysosomes.
Luzio JP, Parkinson MD, Gray SR, Bright NA. Luzio JP, et al. Biochem Soc Trans. 2009 Oct;37(Pt 5):1019-21. doi: 10.1042/BST0371019. Biochem Soc Trans. 2009. PMID: 19754443 Review.
Endosome-lysosome fusion.
Luzio JP, Gray SR, Bright NA. Luzio JP, et al. Biochem Soc Trans. 2010 Dec;38(6):1413-6. doi: 10.1042/BST0381413. Biochem Soc Trans. 2010. PMID: 21118098
185 results