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Cellular Uptake of a Fluorescent Ligand Reveals Ghrelin O-Acyltransferase Interacts with Extracellular Peptides and Exhibits Unexpected Localization for a Secretory Pathway Enzyme.
Campaña MB, Davis TR, Novak SX, Cleverdon ER, Bates M, Krishnan N, Curtis ER, Childs MD, Pierce MR, Morales-Rodriguez Y, Sieburg MA, Hehnly H, Luyt LG, Hougland JL. Campaña MB, et al. Among authors: luyt lg. ACS Chem Biol. 2023 Aug 18;18(8):1880-1890. doi: 10.1021/acschembio.3c00334. Epub 2023 Jul 26. ACS Chem Biol. 2023. PMID: 37494676 Free PMC article.
Ghrelin proteolysis increases in plasma of men, but not women, with obesity.
Fittipaldi AS, Castrogiovanni D, Lufrano D, Saenz C, De Francesco PN, Lalonde T, Luyt LG, Cantel S, Fehrentz JA, Andreoli MF, Perello M. Fittipaldi AS, et al. Among authors: luyt lg. Life Sci. 2023 Jan 15;313:121305. doi: 10.1016/j.lfs.2022.121305. Epub 2022 Dec 18. Life Sci. 2023. PMID: 36543283
Targeting glioblastoma using a novel peptide specific to a deglycosylated isoform of brevican.
von Spreckelsen N, Fadzen CM, Hartrampf N, Ghotmi Y, Wolfe JM, Dubey S, Yang BY, Kijewski MF, Wang S, Farquhar C, Bergmann S, Zdioruk M, Wasserburg JR, Scott B, Murrell E, Bononi FC, Luyt LG, DiCarli M, Lamfers MLM, Ligon KL, Chiocca EA, Viapiano MS, Pentelute BL, Lawler SE, Cho CF. von Spreckelsen N, et al. Among authors: luyt lg. Adv Ther (Weinh). 2021 Apr;4(4):2000244. doi: 10.1002/adtp.202000244. Epub 2021 Jan 20. Adv Ther (Weinh). 2021. PMID: 33997269 Free PMC article.
69 results