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Discovery of V-0219: A Small-Molecule Positive Allosteric Modulator of the Glucagon-Like Peptide-1 Receptor toward Oral Treatment for "Diabesity".
Decara JM, Vázquez-Villa H, Brea J, Alonso M, Srivastava RK, Orio L, Alén F, Suárez J, Baixeras E, García-Cárceles J, Escobar-Peña A, Lutz B, Rodríguez R, Codesido E, Garcia-Ladona FJ, Bennett TA, Ballesteros JA, Cruces J, Loza MI, Benhamú B, Rodríguez de Fonseca F, López-Rodríguez ML. Decara JM, et al. Among authors: lutz b. J Med Chem. 2022 Apr 14;65(7):5449-5461. doi: 10.1021/acs.jmedchem.1c01842. Epub 2022 Mar 29. J Med Chem. 2022. PMID: 35349261 Free PMC article.
Pharmacological blockade of the fatty acid amide hydrolase (FAAH) alters neural proliferation, apoptosis and gliosis in the rat hippocampus, hypothalamus and striatum in a negative energy context.
Rivera P, Bindila L, Pastor A, Pérez-Martín M, Pavón FJ, Serrano A, de la Torre R, Lutz B, Rodríguez de Fonseca F, Suárez J. Rivera P, et al. Among authors: lutz b. Front Cell Neurosci. 2015 Mar 27;9:98. doi: 10.3389/fncel.2015.00098. eCollection 2015. Front Cell Neurosci. 2015. PMID: 25870539 Free PMC article.
Pharmacological activation of CB2 receptors counteracts the deleterious effect of ethanol on cell proliferation in the main neurogenic zones of the adult rat brain.
Rivera P, Blanco E, Bindila L, Alen F, Vargas A, Rubio L, Pavón FJ, Serrano A, Lutz B, Rodríguez de Fonseca F, Suárez J. Rivera P, et al. Among authors: lutz b. Front Cell Neurosci. 2015 Sep 29;9:379. doi: 10.3389/fncel.2015.00379. eCollection 2015. Front Cell Neurosci. 2015. PMID: 26483633 Free PMC article.
Exposure to a Highly Caloric Palatable Diet During Pregestational and Gestational Periods Affects Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Adiposity and Anxiety-Like Behaviors in Male Rat Offspring.
Ramírez-López MT, Vázquez M, Bindila L, Lomazzo E, Hofmann C, Blanco RN, Alén F, Antón M, Decara J, Ouro D, Orio L, Suarez J, Lutz B, Rodríguez de Fonseca F, Gómez de Heras R. Ramírez-López MT, et al. Among authors: lutz b. Front Behav Neurosci. 2016 Jan 6;9:339. doi: 10.3389/fnbeh.2015.00339. eCollection 2015. Front Behav Neurosci. 2016. PMID: 26778987 Free PMC article.
Maternal Caloric Restriction Implemented during the Preconceptional and Pregnancy Period Alters Hypothalamic and Hippocampal Endocannabinoid Levels at Birth and Induces Overweight and Increased Adiposity at Adulthood in Male Rat Offspring.
Ramírez-López MT, Vázquez M, Bindila L, Lomazzo E, Hofmann C, Blanco RN, Alén F, Antón M, Decara J, Arco R, Ouro D, Orio L, Suárez J, Lutz B, Gómez de Heras R, Rodríguez de Fonseca F. Ramírez-López MT, et al. Among authors: lutz b. Front Behav Neurosci. 2016 Nov 1;10:208. doi: 10.3389/fnbeh.2016.00208. eCollection 2016. Front Behav Neurosci. 2016. PMID: 27847471 Free PMC article.
A moderate diet restriction during pregnancy alters the levels of endocannabinoids and endocannabinoid-related lipids in the hypothalamus, hippocampus and olfactory bulb of rat offspring in a sex-specific manner.
Ramírez-López MT, Vázquez M, Lomazzo E, Hofmann C, Blanco RN, Alén F, Antón M, Decara J, Arco R, Orio L, Suárez J, Lutz B, Gómez de Heras R, Bindila L, Rodríguez de Fonseca F. Ramírez-López MT, et al. Among authors: lutz b. PLoS One. 2017 Mar 27;12(3):e0174307. doi: 10.1371/journal.pone.0174307. eCollection 2017. PLoS One. 2017. PMID: 28346523 Free PMC article.
Erratum to "Oleoylethanolamide restores alcohol-induced inhibition of neuronal proliferation and microglial activity in striatum" [Neuropharmacology 146 (2019) 184-197].
Rivera P, Silva-Peña D, Blanco E, Vargas A, Arrabal S, Serrano A, Pavón FJ, Bindila L, Lutz B, Rodríguez de Fonseca F, Suárez J. Rivera P, et al. Among authors: lutz b. Neuropharmacology. 2019 Dec 1;160:107708. doi: 10.1016/j.neuropharm.2019.107708. Epub 2019 Jul 17. Neuropharmacology. 2019. PMID: 31324394 No abstract available.
Adipocyte cannabinoid CB1 receptor deficiency alleviates high fat diet-induced memory deficit, depressive-like behavior, neuroinflammation and impairment in adult neurogenesis.
Suárez J, Rivera P, Aparisi Rey A, Pérez-Martín M, Arrabal S, Rodríguez de Fonseca F, Ruiz de Azua I, Lutz B. Suárez J, et al. Among authors: lutz b. Psychoneuroendocrinology. 2019 Dec;110:104418. doi: 10.1016/j.psyneuen.2019.104418. Epub 2019 Aug 23. Psychoneuroendocrinology. 2019. PMID: 31491589
781 results