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Hepatic IRF3 fuels dysglycemia in obesity through direct regulation of Ppp2r1b.
Patel SJ, Liu N, Piaker S, Gulko A, Andrade ML, Heyward FD, Sermersheim T, Edinger N, Srinivasan H, Emont MP, Westcott GP, Luther J, Chung RT, Yan S, Kumari M, Thomas R, Deleye Y, Tchernof A, White PJ, Baselli GA, Meroni M, De Jesus DF, Ahmad R, Kulkarni RN, Valenti L, Tsai L, Rosen ED. Patel SJ, et al. Among authors: luther j. Sci Transl Med. 2022 Mar 23;14(637):eabh3831. doi: 10.1126/scitranslmed.abh3831. Epub 2022 Mar 23. Sci Transl Med. 2022. PMID: 35320000 Free PMC article.
Hepatic gap junctions amplify alcohol liver injury by propagating cGAS-mediated IRF3 activation.
Luther J, Khan S, Gala MK, Kedrin D, Sridharan G, Goodman RP, Garber JJ, Masia R, Diagacomo E, Adams D, King KR, Piaker S, Reinecker HC, Yarmush ML, Argemi J, Bataller R, Dienstag JL, Chung RT, Patel SJ. Luther J, et al. Proc Natl Acad Sci U S A. 2020 May 26;117(21):11667-11673. doi: 10.1073/pnas.1911870117. Epub 2020 May 11. Proc Natl Acad Sci U S A. 2020. PMID: 32393626 Free PMC article.
A Novel Resolvin-Based Strategy for Limiting Acetaminophen Hepatotoxicity.
Patel SJ, Luther J, Bohr S, Iracheta-Vellve A, Li M, King KR, Chung RT, Yarmush ML. Patel SJ, et al. Among authors: luther j. Clin Transl Gastroenterol. 2016 Mar 17;7(3):e153. doi: 10.1038/ctg.2016.13. Clin Transl Gastroenterol. 2016. PMID: 26986653 Free PMC article.
Hepatic connexin 32 associates with nonalcoholic fatty liver disease severity.
Luther J, Gala MK, Borren N, Masia R, Goodman RP, Moeller IH, DiGiacomo E, Ehrlich A, Warren A, Yarmush ML, Ananthakrishnan A, Corey K, Kaplan LM, Bhatia S, Chung RT, Patel SJ. Luther J, et al. Hepatol Commun. 2018 Jul 16;2(7):786-797. doi: 10.1002/hep4.1179. eCollection 2018 Jul. Hepatol Commun. 2018. PMID: 30202815 Free PMC article.
Peptide-based urinary monitoring of fibrotic nonalcoholic steatohepatitis by mass-barcoded activity-based sensors.
Cazanave SC, Warren AD, Pacula M, Touti F, Zagorska A, Gural N, Huang EK, Sherman S, Cheema M, Ibarra S, Bates J, Billin AN, Liles JT, Budas GR, Breckenridge DG, Tiniakos D, Ratziu V, Daly AK, Govaere O, Anstee QM, Gelrud L, Luther J, Chung RT, Corey KE, Winckler W, Bhatia S, Kwong GA. Cazanave SC, et al. Among authors: luther j. Sci Transl Med. 2021 Oct 20;13(616):eabe8939. doi: 10.1126/scitranslmed.abe8939. Epub 2021 Oct 20. Sci Transl Med. 2021. PMID: 34669440
487 results