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Immune Checkpoint Inhibitor Therapy Aggravates T Cell-Driven Plaque Inflammation in Atherosclerosis.
Poels K, van Leent MMT, Boutros C, Tissot H, Roy S, Meerwaldt AE, Toner YCA, Reiche ME, Kusters PJH, Malinova T, Huveneers S, Kaufman AE, Mani V, Fayad ZA, de Winther MPJ, Marabelle A, Mulder WJM, Robert C, Seijkens TTP, Lutgens E. Poels K, et al. Among authors: lutgens e. JACC CardioOncol. 2020 Oct 6;2(4):599-610. doi: 10.1016/j.jaccao.2020.08.007. eCollection 2020 Nov. JACC CardioOncol. 2020. PMID: 34396271 Free PMC article.
Disruption of the cathepsin K gene reduces atherosclerosis progression and induces plaque fibrosis but accelerates macrophage foam cell formation.
Lutgens E, Lutgens SP, Faber BC, Heeneman S, Gijbels MM, de Winther MP, Frederik P, van der Made I, Daugherty A, Sijbers AM, Fisher A, Long CJ, Saftig P, Black D, Daemen MJ, Cleutjens KB. Lutgens E, et al. Among authors: lutgens sp. Circulation. 2006 Jan 3;113(1):98-107. doi: 10.1161/CIRCULATIONAHA.105.561449. Epub 2005 Dec 19. Circulation. 2006. PMID: 16365196
Liposome-enhanced MRI of neointimal lesions in the ApoE-KO mouse.
Mulder WJ, Douma K, Koning GA, van Zandvoort MA, Lutgens E, Daemen MJ, Nicolay K, Strijkers GJ. Mulder WJ, et al. Among authors: lutgens e. Magn Reson Med. 2006 May;55(5):1170-4. doi: 10.1002/mrm.20883. Magn Reson Med. 2006. PMID: 16598732 Free article.
The immunobiology of CD154-CD40-TRAF interactions in atherosclerosis.
Engel D, Seijkens T, Poggi M, Sanati M, Thevissen L, Beckers L, Wijnands E, Lievens D, Lutgens E. Engel D, et al. Among authors: lutgens e. Semin Immunol. 2009 Oct;21(5):308-12. doi: 10.1016/j.smim.2009.06.004. Epub 2009 Jul 17. Semin Immunol. 2009. PMID: 19616449 Review.
Deficient CD40-TRAF6 signaling in leukocytes prevents atherosclerosis by skewing the immune response toward an antiinflammatory profile.
Lutgens E, Lievens D, Beckers L, Wijnands E, Soehnlein O, Zernecke A, Seijkens T, Engel D, Cleutjens J, Keller AM, Naik SH, Boon L, Oufella HA, Mallat Z, Ahonen CL, Noelle RJ, de Winther MP, Daemen MJ, Biessen EA, Weber C. Lutgens E, et al. J Exp Med. 2010 Feb 15;207(2):391-404. doi: 10.1084/jem.20091293. Epub 2010 Jan 25. J Exp Med. 2010. PMID: 20100871 Free PMC article.
The role of CD154 in haematopoietic development.
Seijkens T, Engel D, Tjwa M, Lutgens E. Seijkens T, et al. Among authors: lutgens e. Thromb Haemost. 2010 Oct;104(4):693-701. doi: 10.1160/TH10-03-0174. Epub 2010 Aug 5. Thromb Haemost. 2010. PMID: 20694278 Review.
240 results