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New Hybrids of 4-Amino-2,3-polymethylene-quinoline and p-Tolylsulfonamide as Dual Inhibitors of Acetyl- and Butyrylcholinesterase and Potential Multifunctional Agents for Alzheimer's Disease Treatment.
Makhaeva GF, Kovaleva NV, Boltneva NP, Lushchekina SV, Astakhova TY, Rudakova EV, Proshin AN, Serkov IV, Radchenko EV, Palyulin VA, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: lushchekina sv. Molecules. 2020 Aug 27;25(17):3915. doi: 10.3390/molecules25173915. Molecules. 2020. PMID: 32867324 Free PMC article.
Synthesis, molecular docking and biological evaluation of N,N-disubstituted 2-aminothiazolines as a new class of butyrylcholinesterase and carboxylesterase inhibitors.
Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Stupina TS, Terentiev AA, Serkov IV, Proshin AN, Bachurin SO, Richardson RJ. Makhaeva GF, et al. Among authors: lushchekina sv. Bioorg Med Chem. 2016 Mar 1;24(5):1050-62. doi: 10.1016/j.bmc.2016.01.031. Epub 2016 Jan 18. Bioorg Med Chem. 2016. PMID: 26827140
Novel conjugates of aminoadamantanes with carbazole derivatives as potential multitarget agents for AD treatment.
Bachurin SO, Shevtsova EF, Makhaeva GF, Grigoriev VV, Boltneva NP, Kovaleva NV, Lushchekina SV, Shevtsov PN, Neganova ME, Redkozubova OM, Bovina EV, Gabrelyan AV, Fisenko VP, Sokolov VB, Aksinenko AY, Echeverria V, Barreto GE, Aliev G. Bachurin SO, et al. Among authors: lushchekina sv. Sci Rep. 2017 Mar 30;7:45627. doi: 10.1038/srep45627. Sci Rep. 2017. PMID: 28358144 Free PMC article.
Synthesis, molecular docking, and biological activity of polyfluoroalkyl dihydroazolo[5,1-c][1,2,4]triazines as selective carboxylesterase inhibitors.
Shchegol'kov EV, Makhaeva GF, Boltneva NP, Lushchekina SV, Serebryakova OG, Rudakova EV, Kovaleva NV, Burgart YV, Saloutin VI, Chupakhin ON, Bachurin SO, Richardson RJ. Shchegol'kov EV, et al. Among authors: lushchekina sv. Bioorg Med Chem. 2017 Aug 1;25(15):3997-4007. doi: 10.1016/j.bmc.2017.05.045. Epub 2017 May 20. Bioorg Med Chem. 2017. PMID: 28578994
9-Substituted acridine derivatives as acetylcholinesterase and butyrylcholinesterase inhibitors possessing antioxidant activity for Alzheimer's disease treatment.
Makhaeva GF, Lushchekina SV, Boltneva NP, Serebryakova OG, Rudakova EV, Ustyugov AA, Bachurin SO, Shchepochkin AV, Chupakhin ON, Charushin VN, Richardson RJ. Makhaeva GF, et al. Among authors: lushchekina sv. Bioorg Med Chem. 2017 Nov 1;25(21):5981-5994. doi: 10.1016/j.bmc.2017.09.028. Epub 2017 Sep 20. Bioorg Med Chem. 2017. PMID: 28986116
Synthesis, molecular docking, and biological activity of 2-vinyl chromones: Toward selective butyrylcholinesterase inhibitors for potential Alzheimer's disease therapeutics.
Makhaeva GF, Boltneva NP, Lushchekina SV, Rudakova EV, Serebryakova OG, Kulikova LN, Beloglazkin AA, Borisov RS, Richardson RJ. Makhaeva GF, et al. Among authors: lushchekina sv. Bioorg Med Chem. 2018 Sep 1;26(16):4716-4725. doi: 10.1016/j.bmc.2018.08.010. Epub 2018 Aug 6. Bioorg Med Chem. 2018. PMID: 30104121
77 results