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Gut microbial co-metabolite 2-methylbutyrylcarnitine exacerbates thrombosis via binding to and activating integrin α2β1.
Huang K, Li Z, He X, Dai J, Huang B, Shi Y, Fan D, Zhang Z, Liu Y, Li N, Zhang Z, Peng J, Liu C, Zeng R, Cen Z, Wang T, Yang W, Cen M, Li J, Yuan S, Zhang L, Hu D, Huang S, Chen P, Lai P, Lin L, Wen J, Zhao Z, Huang X, Yuan L, Zhou L, Wu H, Huang L, Feng K, Wang J, Liao B, Cai W, Deng X, Li Y, Li J, Hu Z, Yang L, Li J, Zhuo Y, Zhang F, Lin L, Luo Y, Zhang W, Ni Q, Hong X, Chang G, Zhang Y, Guan D, Cai W, Lu Y, Li F, Yan L, Ren M, Li L, Chen S. Huang K, et al. Among authors: luo y. Cell Metab. 2024 Mar 5;36(3):598-616.e9. doi: 10.1016/j.cmet.2024.01.014. Epub 2024 Feb 23. Cell Metab. 2024. PMID: 38401546
C-to-G editing generates double-strand breaks causing deletion, transversion and translocation.
Huang ME, Qin Y, Shang Y, Hao Q, Zhan C, Lian C, Luo S, Liu LD, Zhang S, Zhang Y, Wo Y, Li N, Wu S, Gui T, Wang B, Luo Y, Cai Y, Liu X, Xu Z, Dai P, Li S, Zhang L, Dong J, Wang J, Zheng X, Xu Y, Sun Y, Wu W, Yeap LS, Meng FL. Huang ME, et al. Among authors: luo s, luo y. Nat Cell Biol. 2024 Feb;26(2):294-304. doi: 10.1038/s41556-023-01342-2. Epub 2024 Jan 23. Nat Cell Biol. 2024. PMID: 38263276
AMPK-mediated phosphorylation on 53BP1 promotes c-NHEJ.
Jiang Y, Dong Y, Luo Y, Jiang S, Meng FL, Tan M, Li J, Zang Y. Jiang Y, et al. Among authors: luo y. Cell Rep. 2021 Feb 16;34(7):108713. doi: 10.1016/j.celrep.2021.108713. Cell Rep. 2021. PMID: 33596428 Free article.
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