Luo Y - Search Results

1

Discovery and Mechanistic Study of Novel Mycobacterium tuberculosis ClpP1P2 Inhibitors.

Yang Y, Zhao N, Xu X, Zhou Y, Luo B, Zhang J, Sui J, Huang J, Qiu Z, Zhang X, Zeng J, Bai L, Bao R, Luo Y. Yang Y, et al. Among authors: luo b, luo y. J Med Chem. 2023 Dec 28;66(24):16597-16614. doi: 10.1021/acs.jmedchem.3c01054. Epub 2023 Dec 13. J Med Chem. 2023. PMID: 38088921

2

Discovery of (Z)-5-(4-methoxybenzylidene)thiazolidine-2,4-dione, a readily available and orally active glitazone for the treatment of concanavalin A-induced acute liver injury of BALB/c mice.

Luo Y, Ma L, Zheng H, Chen L, Li R, He C, Yang S, Ye X, Chen Z, Li Z, Gao Y, Han J, He G, Yang L, Wei Y. Luo Y, et al. J Med Chem. 2010 Jan 14;53(1):273-81. doi: 10.1021/jm901183d. J Med Chem. 2010. PMID: 19904929

3

Structural modification of honokiol, a biphenyl occurring in Magnolia officinalis: the evaluation of honokiol analogues as inhibitors of angiogenesis and for their cytotoxicity and structure-activity relationship.

Ma L, Chen J, Wang X, Liang X, Luo Y, Zhu W, Wang T, Peng M, Li S, Jie S, Peng A, Wei Y, Chen L. Ma L, et al. Among authors: luo y. J Med Chem. 2011 Oct 13;54(19):6469-81. doi: 10.1021/jm200830u. Epub 2011 Sep 8. J Med Chem. 2011. PMID: 21853991

4

Discovery of novel bis-oxazolidinone compounds as potential potent and selective antitubercular agents.

Ang W, Ye W, Sang Z, Liu Y, Yang T, Deng Y, Luo Y, Wei Y. Ang W, et al. Among authors: luo y. Bioorg Med Chem Lett. 2014 Mar 15;24(6):1496-501. doi: 10.1016/j.bmcl.2014.02.025. Epub 2014 Feb 15. Bioorg Med Chem Lett. 2014. PMID: 24582981

5

Discovery of a Teraryl Oxazolidinone Compound (S)-N-((3-(3-Fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5-yl)methyl)acetamide Phosphate as a Novel Antimicrobial Agent with Enhanced Safety Profile and Efficacies.

Yang T, Chen G, Sang Z, Liu Y, Yang X, Chang Y, Long H, Ang W, Tang J, Wang Z, Li G, Yang S, Zhang J, Wei Y, Luo Y. Yang T, et al. Among authors: luo y. J Med Chem. 2015 Aug 27;58(16):6389-409. doi: 10.1021/acs.jmedchem.5b00152. Epub 2015 Aug 17. J Med Chem. 2015. PMID: 26212502

6

Scaffold Hopping Toward Agomelatine: Novel 3, 4-Dihydroisoquinoline Compounds as Potential Antidepressant Agents.

Yang Y, Ang W, Long H, Chang Y, Li Z, Zhou L, Yang T, Deng Y, Luo Y. Yang Y, et al. Among authors: luo y. Sci Rep. 2016 Oct 4;6:34711. doi: 10.1038/srep34711. Sci Rep. 2016. PMID: 27698414 Free PMC article.

7

Structural optimization and structure-activity relationship studies of N-phenyl-7,8-dihydro-6H-pyrimido[5,4-b][1,4]oxazin-4-amine derivatives as a new class of inhibitors of RET and its drug resistance mutants.

Yang J, Chen K, Zhang G, Yang QY, Li YS, Huang SZ, Wang YL, Yang W, Jiang XJ, Yan HX, Zhu JQ, Xiang R, Luo YF, Li WM, Wei YQ, Li LL, Yang SY. Yang J, et al. Eur J Med Chem. 2018 Jan 1;143:1148-1164. doi: 10.1016/j.ejmech.2017.09.018. Epub 2017 Sep 15. Eur J Med Chem. 2018. PMID: 29133048

8

Discovery of novel anti-tuberculosis agents with pyrrolo[1,2-a]quinoxaline-based scaffold.

Wang T, Tang Y, Yang Y, An Q, Sang Z, Yang T, Liu P, Zhang T, Deng Y, Luo Y. Wang T, et al. Among authors: luo y. Bioorg Med Chem Lett. 2018 Jun 15;28(11):2084-2090. doi: 10.1016/j.bmcl.2018.04.043. Epub 2018 May 2. Bioorg Med Chem Lett. 2018. PMID: 29748048

9

Discovery of hybrids of indolin-2-one and nitroimidazole as potent inhibitors against drug-resistant bacteria.

Zhou Y, Ju Y, Yang Y, Sang Z, Wang Z, He G, Yang T, Luo Y. Zhou Y, et al. Among authors: luo y. J Antibiot (Tokyo). 2018 Oct;71(10):887-897. doi: 10.1038/s41429-018-0076-5. Epub 2018 Jul 3. J Antibiot (Tokyo). 2018. PMID: 29968851

10

Design, synthesis and biological evaluation of novel pyrrole derivatives as potential ClpP1P2 inhibitor against Mycobacterium tuberculosis.

Liu P, Yang Y, Ju Y, Tang Y, Sang Z, Chen L, Yang T, An Q, Zhang T, Luo Y. Liu P, et al. Among authors: luo y. Bioorg Chem. 2018 Oct;80:422-432. doi: 10.1016/j.bioorg.2018.06.004. Epub 2018 Jun 4. Bioorg Chem. 2018. PMID: 30005200

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