Lund J - Search Results

1

A factor VIIIa-mimetic bispecific antibody, Mim8, ameliorates bleeding upon severe vascular challenge in hemophilia A mice.

Østergaard H, Lund J, Greisen PJ, Kjellev S, Henriksen A, Lorenzen N, Johansson E, Røder G, Rasch MG, Johnsen LB, Egebjerg T, Lund S, Rahbek-Nielsen H, Gandhi PS, Lamberth K, Loftager M, Andersen LM, Bonde AC, Stavenuiter F, Madsen DE, Li X, Holm TL, Ley CD, Thygesen P, Zhu H, Zhou R, Thorn K, Yang Z, Hermit MB, Bjelke JR, Hansen BG, Hilden I. Østergaard H, et al. Among authors: lund j, lund s. Blood. 2021 Oct 7;138(14):1258-1268. doi: 10.1182/blood.2020010331. Blood. 2021. PMID: 34077951 Free PMC article.

2

Monoclonal antibodies targeting the disintegrin-like domain of ADAMDEC1 modulates the proteolytic activity and enables quantification of ADAMDEC1 protein in human plasma.

Lund J, Elimar Bitsch AM, Grønbech Rasch M, Enoksson M, Troeberg L, Nagase H, Loftager M, Overgaard MT, Petersen HH. Lund J, et al. MAbs. 2018 Jan;10(1):118-128. doi: 10.1080/19420862.2017.1395541. Epub 2017 Nov 29. MAbs. 2018. PMID: 29185848 Free PMC article.

3

The functional role of the autolysis loop in the regulation of factor X upon hemostatic response.

Bonde AC, Lund J, Hansen JJ, Winther JR, Nielsen PF, Zahn S, Tiainen P, Olsen OH, Petersen HH, Bjelke JR. Bonde AC, et al. Among authors: lund j. J Thromb Haemost. 2022 Mar;20(3):589-599. doi: 10.1111/jth.15624. Epub 2022 Jan 3. J Thromb Haemost. 2022. PMID: 34927362 Free article.

4

Site-specific functional roles of the Factor X activation peptide in the intrinsic tenase-mediated Factor X activation.

Carnbring Bonde A, Rosenørn Hansen S, Johansson E, Rose Bjelke J, Lund J. Carnbring Bonde A, et al. Among authors: lund j. FEBS Lett. 2022 Jun;596(12):1567-1575. doi: 10.1002/1873-3468.14321. Epub 2022 Feb 28. FEBS Lett. 2022. PMID: 35181908 Free article.

5

A systematic approach for evaluating the role of surface-exposed loops in trypsin-like serine proteases applied to the 170 loop in coagulation factor VIIa.

Sorensen AB, Greisen PJ, Madsen JJ, Lund J, Andersen G, Wulff-Larsen PG, Pedersen AA, Gandhi PS, Overgaard MT, Østergaard H, Olsen OH. Sorensen AB, et al. Among authors: lund j. Sci Rep. 2022 Mar 8;12(1):3747. doi: 10.1038/s41598-022-07620-7. Sci Rep. 2022. PMID: 35260627 Free PMC article.

6

In vitro effects of combining Mim8 with factor VIII, FVIIa, and activated prothrombin complex concentrates in thrombin generation assays.

Lund J, Jensen K, Burnier L, Ezban M. Lund J, et al. J Thromb Haemost. 2023 Jun;21(6):1493-1502. doi: 10.1016/j.jtha.2023.03.007. Epub 2023 Apr 8. J Thromb Haemost. 2023. PMID: 37037699 Free article.

7

ADAMDEC1 is a metzincin metalloprotease with dampened proteolytic activity.

Lund J, Olsen OH, Sørensen ES, Stennicke HR, Petersen HH, Overgaard MT. Lund J, et al. J Biol Chem. 2013 Jul 19;288(29):21367-21375. doi: 10.1074/jbc.M113.474536. Epub 2013 Jun 10. J Biol Chem. 2013. PMID: 23754285 Free PMC article.

8

Evidence for restricted reactivity of ADAMDEC1 with protein substrates and endogenous inhibitors.

Lund J, Troeberg L, Kjeldal H, Olsen OH, Nagase H, Sørensen ES, Stennicke HR, Petersen HH, Overgaard MT. Lund J, et al. J Biol Chem. 2015 Mar 6;290(10):6620-9. doi: 10.1074/jbc.M114.601724. Epub 2015 Jan 6. J Biol Chem. 2015. PMID: 25564618 Free PMC article.

9

GLP-1-directed NMDA receptor antagonism for obesity treatment.

Petersen J, Ludwig MQ, Juozaityte V, Ranea-Robles P, Svendsen C, Hwang E, Kristensen AW, Fadahunsi N, Lund J, Breum AW, Mathiesen CV, Sachs L, Moreno-Justicia R, Rohlfs R, Ford JC, Douros JD, Finan B, Portillo B, Grose K, Petersen JE, Trauelsen M, Feuchtinger A, DiMarchi RD, Schwartz TW, Deshmukh AS, Thomsen MB, Kohlmeier KA, Williams KW, Pers TH, Frølund B, Strømgaard K, Klein AB, Clemmensen C. Petersen J, et al. Among authors: lund j. Nature. 2024 May 15. doi: 10.1038/s41586-024-07419-8. Online ahead of print. Nature. 2024. PMID: 38750368

10

Standardizing Integrated Oncology and Palliative Care Across Service Levels: Challenges in Demonstrating Effects in a Prospective Controlled Intervention Trial.

Brenne AT, Løhre ET, Knudsen AK, Lund JÅ, Thronæs M, Driller B, Brunelli C, Kaasa S. Brenne AT, et al. Among authors: lund ja. Oncol Ther. 2024 May 14. doi: 10.1007/s40487-024-00278-3. Online ahead of print. Oncol Ther. 2024. PMID: 38744750 Free article.

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