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Design and Optimization of a Nanoparticulate Pore Former as a Multifunctional Coating Excipient for pH Transition-Independent Controlled Release of Weakly Basic Drugs for Oral Drug Delivery.
Pharmaceutics. 2023 Feb 7;15(2):547. doi: 10.3390/pharmaceutics15020547.
Pharmaceutics. 2023.
PMID: 36839869
Free PMC article.
Investigation of a new pH-responsive nanoparticulate pore former for controlled release enteric coating with improved processability and stability.
Chen K, Chang HHR, Shalviri A, Li J, Lugtu-Pe JA, Kane A, Wu XY.
Chen K, et al. Among authors: lugtu pe ja.
Eur J Pharm Biopharm. 2017 Nov;120:116-125. doi: 10.1016/j.ejpb.2017.08.014. Epub 2017 Sep 5.
Eur J Pharm Biopharm. 2017.
PMID: 28887098
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Tailoring Release Profiles of BCS Class II Drugs Using Controlled Release Amorphous Solid Dispersion Beads with Membrane-Reservoir Design: Effect of Pore Former and Coating Levels.
Lugtu-Pe JA, Lin BY, Chen K, Ghaffari A, Kane A, Wu XY.
Lugtu-Pe JA, et al.
Mol Pharm. 2021 Nov 1;18(11):4198-4209. doi: 10.1021/acs.molpharmaceut.1c00623. Epub 2021 Oct 20.
Mol Pharm. 2021.
PMID: 34668379
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Development of controlled release amorphous solid dispersions (CRASD) using polyvinyl acetate-based release retarding materials: Effect of dosage form design.
Lugtu-Pe JA, Ghaffari A, Chen K, Kane A, Wu XY.
Lugtu-Pe JA, et al.
Eur J Pharm Sci. 2018 Nov 1;124:319-327. doi: 10.1016/j.ejps.2018.09.006. Epub 2018 Sep 6.
Eur J Pharm Sci. 2018.
PMID: 30194980
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A combination of pH-sensitive caplet coatings may be an effective noninvasive strategy to deliver bioactive substances, nutrients, or their precursors to the colon.
Aimone AM, Connolly B, Chaudhary S, Lugtu-Pe J, Martinuzzi F, Pencharz P, O'Connor DL.
Aimone AM, et al.
Appl Physiol Nutr Metab. 2009 Oct;34(5):893-900. doi: 10.1139/H09-090.
Appl Physiol Nutr Metab. 2009.
PMID: 19935851
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