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Tailoring vascular phenotype through AAV therapy promotes anti-tumor immunity in glioma.
Ramachandran M, Vaccaro A, van de Walle T, Georganaki M, Lugano R, Vemuri K, Kourougkiaouri D, Vazaios K, Hedlund M, Tsaridou G, Uhrbom L, Pietilä I, Martikainen M, van Hooren L, Olsson Bontell T, Jakola AS, Yu D, Westermark B, Essand M, Dimberg A. Ramachandran M, et al. Among authors: lugano r. Cancer Cell. 2023 Jun 12;41(6):1134-1151.e10. doi: 10.1016/j.ccell.2023.04.010. Epub 2023 May 11. Cancer Cell. 2023. PMID: 37172581 Free article.
Elevated expression of the C-type lectin CD93 in the glioblastoma vasculature regulates cytoskeletal rearrangements that enhance vessel function and reduce host survival.
Langenkamp E, Zhang L, Lugano R, Huang H, Elhassan TE, Georganaki M, Bazzar W, Lööf J, Trendelenburg G, Essand M, Pontén F, Smits A, Dimberg A. Langenkamp E, et al. Among authors: lugano r. Cancer Res. 2015 Nov 1;75(21):4504-16. doi: 10.1158/0008-5472.CAN-14-3636. Epub 2015 Sep 11. Cancer Res. 2015. PMID: 26363010
ELTD1 deletion reduces vascular abnormality and improves T-cell recruitment after PD-1 blockade in glioma.
Huang H, Georganaki M, Conze LL, Laviña B, van Hooren L, Vemuri K, van de Walle T, Ramachandran M, Zhang L, Pontén F, Bergqvist M, Smits A, Betsholtz C, Dejana E, Magnusson PU, He L, Lugano R, Dimberg A. Huang H, et al. Among authors: lugano r. Neuro Oncol. 2022 Mar 12;24(3):398-411. doi: 10.1093/neuonc/noab181. Neuro Oncol. 2022. PMID: 34347079 Free PMC article.
Tumor endothelial cell up-regulation of IDO1 is an immunosuppressive feed-back mechanism that reduces the response to CD40-stimulating immunotherapy.
Georganaki M, Ramachandran M, Tuit S, Núñez NG, Karampatzakis A, Fotaki G, van Hooren L, Huang H, Lugano R, Ulas T, Kaunisto A, Holland EC, Ellmark P, Mangsbo SM, Schultze J, Essand M, Tugues S, Dimberg A. Georganaki M, et al. Among authors: lugano r. Oncoimmunology. 2020 Mar 9;9(1):1730538. doi: 10.1080/2162402X.2020.1730538. eCollection 2020. Oncoimmunology. 2020. PMID: 32231867 Free PMC article.
23 results