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Novel diversity-oriented synthesis-derived respiratory syncytial virus inhibitors identified via a high throughput replicon-based screen.
Duvall JR, VerPlank L, Ludeke B, McLeod SM, Lee MD 4th, Vishwanathan K, Mulrooney CA, Le Quement S, Yu Q, Palmer MA, Fleming P, Fearns R, Foley MA, Scherer CA. Duvall JR, et al. Among authors: ludeke b. Antiviral Res. 2016 Jul;131:19-25. doi: 10.1016/j.antiviral.2016.03.015. Epub 2016 Apr 6. Antiviral Res. 2016. PMID: 27059228 Free PMC article.
Orally Efficacious Broad-Spectrum Ribonucleoside Analog Inhibitor of Influenza and Respiratory Syncytial Viruses.
Yoon JJ, Toots M, Lee S, Lee ME, Ludeke B, Luczo JM, Ganti K, Cox RM, Sticher ZM, Edpuganti V, Mitchell DG, Lockwood MA, Kolykhalov AA, Greninger AL, Moore ML, Painter GR, Lowen AC, Tompkins SM, Fearns R, Natchus MG, Plemper RK. Yoon JJ, et al. Among authors: ludeke b. Antimicrob Agents Chemother. 2018 Jul 27;62(8):e00766-18. doi: 10.1128/AAC.00766-18. Print 2018 Aug. Antimicrob Agents Chemother. 2018. PMID: 29891600 Free PMC article.
Structure of the human metapneumovirus polymerase phosphoprotein complex.
Pan J, Qian X, Lattmann S, El Sahili A, Yeo TH, Jia H, Cressey T, Ludeke B, Noton S, Kalocsay M, Fearns R, Lescar J. Pan J, et al. Among authors: ludeke b. Nature. 2020 Jan;577(7789):275-279. doi: 10.1038/s41586-019-1759-1. Epub 2019 Nov 7. Nature. 2020. PMID: 31698413 Free PMC article.
Structural basis for dimerization of a paramyxovirus polymerase complex.
Xie J, Ouizougun-Oubari M, Wang L, Zhai G, Wu D, Lin Z, Wang M, Ludeke B, Yan X, Nilsson T, Gao L, Huang X, Fearns R, Chen S. Xie J, et al. Among authors: ludeke b. Nat Commun. 2024 Apr 11;15(1):3163. doi: 10.1038/s41467-024-47470-7. Nat Commun. 2024. PMID: 38605025 Free PMC article.
Direct DNA sequencing following SSCP analysis.
Petersen I, Ohgaki H, Ludeke B, Kleihues P. Petersen I, et al. Among authors: ludeke b. Anal Biochem. 1994 May 1;218(2):478-9. doi: 10.1006/abio.1994.1216. Anal Biochem. 1994. PMID: 8074314 No abstract available.
26 results