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BRAFV600E Expression in Thyrocytes Causes Recruitment of Immunosuppressive STABILIN-1 Macrophages.
Spourquet C, Delcorte O, Lemoine P, Dauguet N, Loriot A, Achouri Y, Hollmén M, Jalkanen S, Huaux F, Lucas S, Meerkeeck PV, Knauf JA, Fagin JA, Dessy C, Mourad M, Henriet P, Tyteca D, Marbaix E, Pierreux CE. Spourquet C, et al. Among authors: lucas s. Cancers (Basel). 2022 Sep 26;14(19):4687. doi: 10.3390/cancers14194687. Cancers (Basel). 2022. PMID: 36230610 Free PMC article.
PDGF-D expression is down-regulated by TGFβ in fibroblasts.
Charni Chaabane S, Coomans de Brachène A, Essaghir A, Velghe A, Lo Re S, Stockis J, Lucas S, Khachigian LM, Huaux F, Demoulin JB. Charni Chaabane S, et al. Among authors: lucas s. PLoS One. 2014 Oct 3;9(10):e108656. doi: 10.1371/journal.pone.0108656. eCollection 2014. PLoS One. 2014. PMID: 25280005 Free PMC article.
Combined Blockade of GARP:TGF-β1 and PD-1 Increases Infiltration of T Cells and Density of Pericyte-Covered GARP+ Blood Vessels in Mouse MC38 Tumors.
Bertrand C, Van Meerbeeck P, de Streel G, Vaherto-Bleeckx N, Benhaddi F, Rouaud L, Noël A, Coulie PG, van Baren N, Lucas S. Bertrand C, et al. Among authors: lucas s. Front Immunol. 2021 Jul 27;12:704050. doi: 10.3389/fimmu.2021.704050. eCollection 2021. Front Immunol. 2021. PMID: 34386010 Free PMC article.
Therapeutic activity of GARP:TGF-β1 blockade in murine primary myelofibrosis.
Lecomte S, Devreux J, de Streel G, van Baren N, Havelange V, Schröder D, Vaherto N, Vanhaver C, Vanderaa C, Dupuis N, Pecquet C, Coulie PG, Constantinescu SN, Lucas S. Lecomte S, et al. Among authors: lucas s. Blood. 2023 Feb 2;141(5):490-502. doi: 10.1182/blood.2022017097. Blood. 2023. PMID: 36322928 Free PMC article.
Selective inhibition of TGF-β1 produced by GARP-expressing Tregs overcomes resistance to PD-1/PD-L1 blockade in cancer.
de Streel G, Bertrand C, Chalon N, Liénart S, Bricard O, Lecomte S, Devreux J, Gaignage M, De Boeck G, Mariën L, Van De Walle I, van der Woning B, Saunders M, de Haard H, Vermeersch E, Maes W, Deckmyn H, Coulie PG, van Baren N, Lucas S. de Streel G, et al. Among authors: lucas s. Nat Commun. 2020 Sep 11;11(1):4545. doi: 10.1038/s41467-020-17811-3. Nat Commun. 2020. PMID: 32917858 Free PMC article.
Blocking GARP-mediated activation of TGF-β1 did not alter innate or adaptive immune responses to bacterial infection or protein immunization in mice.
Gaignage M, Zhang X, Stockis J, Dedobbeleer O, Michiels C, Cochez P, Dumoutier L, Coulie PG, Lucas S. Gaignage M, et al. Among authors: lucas s. Cancer Immunol Immunother. 2022 Aug;71(8):1851-1862. doi: 10.1007/s00262-021-03119-8. Epub 2022 Jan 1. Cancer Immunol Immunother. 2022. PMID: 34973084 Free PMC article.
1,751 results