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Caspase-11 promotes high-fat diet-induced NAFLD by increasing glycolysis, OXPHOS, and pyroptosis in macrophages.
Drummer C 4th, Saaoud F, Jhala NC, Cueto R, Sun Y, Xu K, Shao Y, Lu Y, Shen H, Yang L, Zhou Y, Yu J, Wu S, Snyder NW, Hu W, Zhuo J', Zhong Y, Jiang X, Wang H, Yang X. Drummer C 4th, et al. Among authors: lu y. Front Immunol. 2023 Jan 26;14:1113883. doi: 10.3389/fimmu.2023.1113883. eCollection 2023. Front Immunol. 2023. PMID: 36776889 Free PMC article.
Uremic toxins are conditional danger- or homeostasis-associated molecular patterns.
Sun Y, Johnson C, Zhou J, Wang L, Li YF, Lu Y, Nanayakkara G, Fu H, Shao Y, Sanchez C, Yang WY, Wang X, Choi ET, Li R, Wang H, Yang XF. Sun Y, et al. Among authors: lu y. Front Biosci (Landmark Ed). 2018 Jan 1;23(2):348-387. doi: 10.2741/4595. Front Biosci (Landmark Ed). 2018. PMID: 28930551 Free PMC article.
Increasing Upstream Chromatin Long-Range Interactions May Favor Induction of Circular RNAs in LysoPC-Activated Human Aortic Endothelial Cells.
Li A, Sun Y, Drummer C 4th, Lu Y, Yu D, Zhou Y, Li X, Pearson SJ, Johnson C, Yu C, Yang WY, Mastascusa K, Jiang X, Sun J, Rogers T, Hu W, Wang H, Yang X. Li A, et al. Among authors: lu y. Front Physiol. 2019 Apr 18;10:433. doi: 10.3389/fphys.2019.00433. eCollection 2019. Front Physiol. 2019. PMID: 31057422 Free PMC article.
Increased acetylation of H3K14 in the genomic regions that encode trained immunity enzymes in lysophosphatidylcholine-activated human aortic endothelial cells - Novel qualification markers for chronic disease risk factors and conditional DAMPs.
Lu Y, Sun Y, Drummer C 4th, Nanayakkara GK, Shao Y, Saaoud F, Johnson C, Zhang R, Yu D, Li X, Yang WY, Yu J, Jiang X, Choi ET, Wang H, Yang X. Lu Y, et al. Redox Biol. 2019 Jun;24:101221. doi: 10.1016/j.redox.2019.101221. Epub 2019 May 22. Redox Biol. 2019. PMID: 31153039 Free PMC article.
Experimental Data-Mining Analyses Reveal New Roles of Low-Intensity Ultrasound in Differentiating Cell Death Regulatome in Cancer and Non-cancer Cells via Potential Modulation of Chromatin Long-Range Interactions.
Wang J, Lai B, Nanayakkara G, Yang Q, Sun Y, Lu Y, Shao Y, Yu D, Yang WY, Cueto R, Fu H, Zeng H, Shen W, Wu S, Zhang C, Liu Y, Choi ET, Wang H, Yang X. Wang J, et al. Among authors: lu y. Front Oncol. 2019 Jul 12;9:600. doi: 10.3389/fonc.2019.00600. eCollection 2019. Front Oncol. 2019. PMID: 31355136 Free PMC article.
Twenty Novel Disease Group-Specific and 12 New Shared Macrophage Pathways in Eight Groups of 34 Diseases Including 24 Inflammatory Organ Diseases and 10 Types of Tumors.
Lai B, Wang J, Fagenson A, Sun Y, Saredy J, Lu Y, Nanayakkara G, Yang WY, Yu D, Shao Y, Drummer C 4th, Johnson C, Saaoud F, Zhang R, Yang Q, Xu K, Mastascusa K, Cueto R, Fu H, Wu S, Sun L, Zhu P, Qin X, Yu J, Fan D, Shen YH, Sun J, Rogers T, Choi ET, Wang H, Yang X. Lai B, et al. Among authors: lu y. Front Immunol. 2019 Nov 14;10:2612. doi: 10.3389/fimmu.2019.02612. eCollection 2019. Front Immunol. 2019. PMID: 31824480 Free PMC article.
End-stage renal disease is different from chronic kidney disease in upregulating ROS-modulated proinflammatory secretome in PBMCs - A novel multiple-hit model for disease progression.
Zhang R, Saredy J, Shao Y, Yao T, Liu L, Saaoud F, Yang WY, Sun Y, Johnson C, Drummer C 4th, Fu H, Lu Y, Xu K, Liu M, Wang J, Cutler E, Yu D, Jiang X, Li Y, Li R, Wang L, Choi ET, Wang H, Yang X. Zhang R, et al. Among authors: lu y. Redox Biol. 2020 Jul;34:101460. doi: 10.1016/j.redox.2020.101460. Epub 2020 Feb 20. Redox Biol. 2020. PMID: 32179051 Free PMC article.
Vascular Endothelial Cells and Innate Immunity.
Shao Y, Saredy J, Yang WY, Sun Y, Lu Y, Saaoud F, Drummer C 4th, Johnson C, Xu K, Jiang X, Wang H, Yang X. Shao Y, et al. Among authors: lu y. Arterioscler Thromb Vasc Biol. 2020 Jun;40(6):e138-e152. doi: 10.1161/ATVBAHA.120.314330. Epub 2020 May 27. Arterioscler Thromb Vasc Biol. 2020. PMID: 32459541 Free PMC article. Review.
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