Lu T - Search Results

1

Off-the-shelf CAR-engineered natural killer cells targeting FLT3 enhance killing of acute myeloid leukemia.

Mansour AG, Teng KY, Li Z, Zhu Z, Chen H, Tian L, Ali A, Zhang J, Lu T, Ma S, Lin CM, Caligiuri MA, Yu J. Mansour AG, et al. Among authors: lu t. Blood Adv. 2023 Oct 24;7(20):6225-6239. doi: 10.1182/bloodadvances.2022007405. Blood Adv. 2023. PMID: 37379267 Free PMC article.

2

A Synthetic Disaccharide Derivative of Diphyllin, TAARD, Activates Human Natural Killer Cells to Secrete Interferon-Gamma via Toll-Like Receptor-Mediated NF-κB and STAT3 Signaling Pathways.

Yi L, Chen L, Guo X, Lu T, Wang H, Ji X, Zhang J, Ren Y, Pan P, Kinghorn AD, Huang X, Wang LS, Fan Z, Caligiuri MA, Yu J. Yi L, et al. Among authors: lu t. Front Immunol. 2018 Jul 18;9:1509. doi: 10.3389/fimmu.2018.01509. eCollection 2018. Front Immunol. 2018. PMID: 30072983 Free PMC article.

3

Cbl-b Is Upregulated and Plays a Negative Role in Activated Human NK Cells.

Lu T, Chen L, Mansour AG, Yu MJ, Brooks N, Teng KY, Li Z, Zhang J, Barr T, Yu J, Caligiuri MA. Lu T, et al. J Immunol. 2021 Feb 15;206(4):677-685. doi: 10.4049/jimmunol.2000177. Epub 2021 Jan 8. J Immunol. 2021. PMID: 33419766 Free PMC article.

4

An Oncolytic Virus Expressing IL15/IL15Rα Combined with Off-the-Shelf EGFR-CAR NK Cells Targets Glioblastoma.

Ma R, Lu T, Li Z, Teng KY, Mansour AG, Yu M, Tian L, Xu B, Ma S, Zhang J, Barr T, Peng Y, Caligiuri MA, Yu J. Ma R, et al. Among authors: lu t. Cancer Res. 2021 Jul 1;81(13):3635-3648. doi: 10.1158/0008-5472.CAN-21-0035. Epub 2021 May 18. Cancer Res. 2021. PMID: 34006525 Free PMC article.

5

Hijacking TYRO3 from Tumor Cells via Trogocytosis Enhances NK-cell Effector Functions and Proliferation.

Lu T, Ma R, Li Z, Mansour AG, Teng KY, Chen L, Zhang J, Barr T, Caligiuri MA, Yu J. Lu T, et al. Cancer Immunol Res. 2021 Oct;9(10):1229-1241. doi: 10.1158/2326-6066.CIR-20-1014. Epub 2021 Jul 29. Cancer Immunol Res. 2021. PMID: 34326137 Free PMC article.

6

Off-the-Shelf Prostate Stem Cell Antigen-Directed Chimeric Antigen Receptor Natural Killer Cell Therapy to Treat Pancreatic Cancer.

Teng KY, Mansour AG, Zhu Z, Li Z, Tian L, Ma S, Xu B, Lu T, Chen H, Hou D, Zhang J, Priceman SJ, Caligiuri MA, Yu J. Teng KY, et al. Among authors: lu t. Gastroenterology. 2022 Apr;162(4):1319-1333. doi: 10.1053/j.gastro.2021.12.281. Epub 2022 Jan 6. Gastroenterology. 2022. PMID: 34999097 Free PMC article.

7

PDGF-D-PDGFRβ signaling enhances IL-15-mediated human natural killer cell survival.

Ma S, Tang T, Wu X, Mansour AG, Lu T, Zhang J, Wang LS, Caligiuri MA, Yu J. Ma S, et al. Among authors: lu t. Proc Natl Acad Sci U S A. 2022 Jan 18;119(3):e2114134119. doi: 10.1073/pnas.2114134119. Proc Natl Acad Sci U S A. 2022. PMID: 35027451 Free PMC article.

8

B7H6 Serves as a Negative Prognostic Marker and an Immune Modulator in Human Pancreatic Cancer.

Zhu Z, Teng KY, Zhou J, Xu Y, Zhang L, Zhao H, Zhang X, Tian L, Li Z, Lu T, Ma S, Li Z, Dai Z, Wang J, Chen X, Wu X, Pan Y, Shi W, You Z, Chen H, Chung V, Yu J, He S, Zhao X, Cao L, Li D. Zhu Z, et al. Among authors: lu t. Front Oncol. 2022 Mar 3;12:814312. doi: 10.3389/fonc.2022.814312. eCollection 2022. Front Oncol. 2022. PMID: 35311080 Free PMC article.

9

ILC1s control leukemia stem cell fate and limit development of AML.

Li Z, Ma R, Ma S, Tian L, Lu T, Zhang J, Mundy-Bosse BL, Zhang B, Marcucci G, Caligiuri MA, Yu J. Li Z, et al. Among authors: lu t. Nat Immunol. 2022 May;23(5):718-730. doi: 10.1038/s41590-022-01198-y. Epub 2022 Apr 29. Nat Immunol. 2022. PMID: 35487987 Free PMC article.

10

Off-the-shelf CAR natural killer cells secreting IL-15 target spike in treating COVID-19.

Lu T, Ma R, Dong W, Teng KY, Kollath DS, Li Z, Yi J, Bustillos C, Ma S, Tian L, Mansour AG, Li Z, Settles EW, Zhang J, Keim PS, Barker BM, Caligiuri MA, Yu J. Lu T, et al. Nat Commun. 2022 May 11;13(1):2576. doi: 10.1038/s41467-022-30216-8. Nat Commun. 2022. PMID: 35546150 Free PMC article.

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