Lu T - Search Results

1

Genomic atlas of the plasma metabolome prioritizes metabolites implicated in human diseases.

Chen Y, Lu T, Pettersson-Kymmer U, Stewart ID, Butler-Laporte G, Nakanishi T, Cerani A, Liang KYH, Yoshiji S, Willett JDS, Su CY, Raina P, Greenwood CMT, Farjoun Y, Forgetta V, Langenberg C, Zhou S, Ohlsson C, Richards JB. Chen Y, et al. Among authors: lu t. Nat Genet. 2023 Jan;55(1):44-53. doi: 10.1038/s41588-022-01270-1. Epub 2023 Jan 12. Nat Genet. 2023. PMID: 36635386 Free PMC article.

2

Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis.

Lu T, Klein KO, Colmegna I, Lora M, Greenwood CMT, Hudson M. Lu T, et al. BMC Med Genomics. 2019 Oct 24;12(1):144. doi: 10.1186/s12920-019-0602-8. BMC Med Genomics. 2019. PMID: 31651337 Free PMC article.

3

Polygenic risk for coronary heart disease acts through atherosclerosis in type 2 diabetes.

Lu T, Forgetta V, Yu OHY, Mokry L, Gregory M, Thanassoulis G, Greenwood CMT, Richards JB. Lu T, et al. Cardiovasc Diabetol. 2020 Jan 30;19(1):12. doi: 10.1186/s12933-020-0988-9. Cardiovasc Diabetol. 2020. PMID: 32000781 Free PMC article.

4

Simultaneous SNP selection and adjustment for population structure in high dimensional prediction models.

Bhatnagar SR, Yang Y, Lu T, Schurr E, Loredo-Osti JC, Forest M, Oualkacha K, Greenwood CMT. Bhatnagar SR, et al. Among authors: lu t. PLoS Genet. 2020 May 4;16(5):e1008766. doi: 10.1371/journal.pgen.1008766. eCollection 2020 May. PLoS Genet. 2020. PMID: 32365090 Free PMC article.

5

Individuals with common diseases but with a low polygenic risk score could be prioritized for rare variant screening.

Lu T, Zhou S, Wu H, Forgetta V, Greenwood CMT, Richards JB. Lu T, et al. Genet Med. 2021 Mar;23(3):508-515. doi: 10.1038/s41436-020-01007-7. Epub 2020 Oct 28. Genet Med. 2021. PMID: 33110269 Free article.

6

Improved prediction of fracture risk leveraging a genome-wide polygenic risk score.

Lu T, Forgetta V, Keller-Baruch J, Nethander M, Bennett D, Forest M, Bhatnagar S, Walters RG, Lin K, Chen Z, Li L, Karlsson M, Mellström D, Orwoll E, McCloskey EV, Kanis JA, Leslie WD, Clarke RJ, Ohlsson C, Greenwood CMT, Richards JB. Lu T, et al. Genome Med. 2021 Feb 3;13(1):16. doi: 10.1186/s13073-021-00838-6. Genome Med. 2021. PMID: 33536041 Free PMC article.

7

A Polygenic Risk Score to Predict Future Adult Short Stature Among Children.

Lu T, Forgetta V, Wu H, Perry JRB, Ong KK, Greenwood CMT, Timpson NJ, Manousaki D, Richards JB. Lu T, et al. J Clin Endocrinol Metab. 2021 Jun 16;106(7):1918-1928. doi: 10.1210/clinem/dgab215. J Clin Endocrinol Metab. 2021. PMID: 33788949 Free PMC article.

8

Detecting cord blood cell type-specific epigenetic associations with gestational diabetes mellitus and early childhood growth.

Lu T, Cardenas A, Perron P, Hivert MF, Bouchard L, Greenwood CMT. Lu T, et al. Clin Epigenetics. 2021 Jun 26;13(1):131. doi: 10.1186/s13148-021-01114-5. Clin Epigenetics. 2021. PMID: 34174944 Free PMC article.

9

Block coordinate descent algorithm improves variable selection and estimation in error-in-variables regression.

Escribe C, Lu T, Keller-Baruch J, Forgetta V, Xiao B, Richards JB, Bhatnagar S, Oualkacha K, Greenwood CMT. Escribe C, et al. Among authors: lu t. Genet Epidemiol. 2021 Dec;45(8):874-890. doi: 10.1002/gepi.22430. Epub 2021 Sep 1. Genet Epidemiol. 2021. PMID: 34468045 Free PMC article.

10

Polygenic risk score as a possible tool for identifying familial monogenic causes of complex diseases.

Lu T, Forgetta V, Richards JB, Greenwood CMT. Lu T, et al. Genet Med. 2022 Jul;24(7):1545-1555. doi: 10.1016/j.gim.2022.03.022. Epub 2022 Apr 23. Genet Med. 2022. PMID: 35460399 Free article.

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