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Selective decrease of donor-reactive Tregs after liver transplantation limits Treg therapy for promoting allograft tolerance in humans.
Tang Q, Leung J, Peng Y, Sanchez-Fueyo A, Lozano JJ, Lam A, Lee K, Greenland JR, Hellerstein M, Fitch M, Li KW, Esensten JH, Putnam AL, Lares A, Nguyen V, Liu W, Bridges ND, Odim J, Demetris AJ, Levitsky J, Taner T, Feng S. Tang Q, et al. Among authors: lozano jj. Sci Transl Med. 2022 Nov 2;14(669):eabo2628. doi: 10.1126/scitranslmed.abo2628. Epub 2022 Nov 2. Sci Transl Med. 2022. PMID: 36322627 Free PMC article. Clinical Trial.
Dysregulated anti-oxidant signalling and compromised mitochondrial integrity negatively influence regulatory T cell function and viability in liver disease.
Vaikunthanathan T, Landmann E, Correa DM, Romano M, Trevelin SC, Peng Q, Crespo E, Corrado M, Lozano JJ, Pearce EL, Perpinan E, Zoccarato A, Siew L, Edwards-Hicks J, Khan R, Luu NT, Thursz MR, Newsome PN, Martinez-Llordella M, Shah N, Lechler RI, Shah AM, Sanchez-Fueyo A, Lombardi G, Safinia N. Vaikunthanathan T, et al. Among authors: lozano jj. EBioMedicine. 2023 Sep;95:104778. doi: 10.1016/j.ebiom.2023.104778. Epub 2023 Aug 30. EBioMedicine. 2023. PMID: 37657135 Free PMC article.
Neddylation orchestrates the complex transcriptional and posttranscriptional program that drives Schwann cell myelination.
Ayuso-García P, Sánchez-Rueda A, Velasco-Avilés S, Tamayo-Caro M, Ferrer-Pinós A, Huarte-Sebastian C, Alvarez V, Riobello C, Jiménez-Vega S, Buendia I, Cañas-Martin J, Fernández-Susavila H, Aparicio-Rey A, Esquinas-Román EM, Ponte CR, Guhl R, Laville N, Pérez-Andrés E, Lavín JL, González-Lopez M, Cámara NM, Aransay AM, Lozano JJ, Sutherland JD, Barrio R, Martinez-Chantar ML, Azkargorta M, Elortza F, Soriano-Navarro M, Matute C, Sánchez-Gómez MV, Bayón-Cordero L, Pérez-Samartín A, Bravo SB, Kurz T, Lama-Díaz T, Blanco MG, Haddad S, Record CJ, van Hasselt PM, Reilly MM, Varela-Rey M, Woodhoo A. Ayuso-García P, et al. Among authors: lozano jj. Sci Adv. 2024 Apr 12;10(15):eadm7600. doi: 10.1126/sciadv.adm7600. Epub 2024 Apr 12. Sci Adv. 2024. PMID: 38608019 Free PMC article.
Inflammatory macrophages reprogram to immunosuppression by reducing mitochondrial translation.
Cortés M, Brischetto A, Martinez-Campanario MC, Ninfali C, Domínguez V, Fernández S, Celis R, Esteve-Codina A, Lozano JJ, Sidorova J, Garrabou G, Siegert AM, Enrich C, Pintado B, Morales-Ruiz M, Castro P, Cañete JD, Postigo A. Cortés M, et al. Among authors: lozano jj. Nat Commun. 2023 Nov 17;14(1):7471. doi: 10.1038/s41467-023-42277-4. Nat Commun. 2023. PMID: 37978290 Free PMC article.
Long Non-Coding RNA Signatures in the Ileum and Colon of Crohn's Disease Patients and Effect of Anti-TNF-α Treatment on Their Modulation.
Baldan-Martin M, Rubín de Célix C, Orejudo M, Ortega Moreno L, Fernández-Tomé S, Soleto I, Ramirez C, Arroyo R, Fernández P, Santander C, Moreno-Monteagudo JA, Casanova MJ, Casals F, Casabona S, Becerro I, Lozano JJ, Aransay AM, Chaparro M, Gisbert JP. Baldan-Martin M, et al. Among authors: lozano jj. Int J Mol Sci. 2023 Oct 28;24(21):15691. doi: 10.3390/ijms242115691. Int J Mol Sci. 2023. PMID: 37958675 Free PMC article.
Quantification of rare somatic single nucleotide variants by droplet digital PCR using SuperSelective primers.
Pablo-Fontecha V, Hernández-Illán E, Reparaz A, Asensio E, Morata J, Tonda R, Lahoz S, Parra C, Lozano JJ, García-Heredia A, Martínez-Roca A, Beltran S, Balaguer F, Jover R, Castells A, Trullàs R, Podlesniy P, Camps J. Pablo-Fontecha V, et al. Among authors: lozano jj. Sci Rep. 2023 Nov 3;13(1):18997. doi: 10.1038/s41598-023-39874-0. Sci Rep. 2023. PMID: 37923774 Free PMC article.
The EMT factor ZEB1 paradoxically inhibits EMT in BRAF-mutant carcinomas.
Sánchez-Tilló E, Pedrosa L, Vila I, Chen Y, Győrffy B, Sánchez-Moral L, Siles L, Lozano JJ, Esteve-Codina A, Darling DS, Cuatrecasas M, Castells A, Maurel J, Postigo A. Sánchez-Tilló E, et al. Among authors: lozano jj. JCI Insight. 2023 Oct 23;8(20):e164629. doi: 10.1172/jci.insight.164629. JCI Insight. 2023. PMID: 37870961 Free PMC article.
Transcriptomics and translatomics identify a robust inflammatory gene signature in brain endothelial cells after ischemic stroke.
Arbaizar-Rovirosa M, Gallizioli M, Lozano JJ, Sidorova J, Pedragosa J, Figuerola S, Chaparro-Cabanillas N, Boya P, Graupera M, Claret M, Urra X, Planas AM. Arbaizar-Rovirosa M, et al. Among authors: lozano jj. J Neuroinflammation. 2023 Sep 11;20(1):207. doi: 10.1186/s12974-023-02888-6. J Neuroinflammation. 2023. PMID: 37691115 Free PMC article.
225 results