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A preclinical platform for assessing antitumor effects and systemic toxicities of cancer drug targets.
Li X, Huang CH, Sánchez-Rivera FJ, Kennedy MC, Tschaharganeh DF, Morris JP 4th, Montinaro A, O'Rourke KP, Banito A, Wilkinson JE, Chen CC, Ho YJ, Dow LE, Tian S, Luan W, de Stanchina E, Zhang T, Gray NS, Walczak H, Lowe SW. Li X, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2022 Apr 26;119(17):e2110557119. doi: 10.1073/pnas.2110557119. Epub 2022 Apr 20. Proc Natl Acad Sci U S A. 2022. PMID: 35442775 Free PMC article.
Oncogenic ras and p53 cooperate to induce cellular senescence.
Ferbeyre G, de Stanchina E, Lin AW, Querido E, McCurrach ME, Hannon GJ, Lowe SW. Ferbeyre G, et al. Among authors: lowe sw. Mol Cell Biol. 2002 May;22(10):3497-508. doi: 10.1128/MCB.22.10.3497-3508.2002. Mol Cell Biol. 2002. PMID: 11971980 Free PMC article.
Tumour suppression: something for nothing?
de Stanchina E, Lowe SW. de Stanchina E, et al. Among authors: lowe sw. Nat Cell Biol. 2002 Dec;4(12):E275-6. doi: 10.1038/ncb1202-e275. Nat Cell Biol. 2002. PMID: 12461528 No abstract available.
Survival signalling by Akt and eIF4E in oncogenesis and cancer therapy.
Wendel HG, De Stanchina E, Fridman JS, Malina A, Ray S, Kogan S, Cordon-Cardo C, Pelletier J, Lowe SW. Wendel HG, et al. Among authors: lowe sw. Nature. 2004 Mar 18;428(6980):332-7. doi: 10.1038/nature02369. Nature. 2004. PMID: 15029198 Free article.
Loss of p53 impedes the antileukemic response to BCR-ABL inhibition.
Wendel HG, de Stanchina E, Cepero E, Ray S, Emig M, Fridman JS, Veach DR, Bornmann WG, Clarkson B, McCombie WR, Kogan SC, Hochhaus A, Lowe SW. Wendel HG, et al. Among authors: lowe sw. Proc Natl Acad Sci U S A. 2006 May 9;103(19):7444-9. doi: 10.1073/pnas.0602402103. Epub 2006 May 1. Proc Natl Acad Sci U S A. 2006. PMID: 16651519 Free PMC article.
370 results