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MLL3 is a haploinsufficient 7q tumor suppressor in acute myeloid leukemia.
Chen C, Liu Y, Rappaport AR, Kitzing T, Schultz N, Zhao Z, Shroff AS, Dickins RA, Vakoc CR, Bradner JE, Stock W, LeBeau MM, Shannon KM, Kogan S, Zuber J, Lowe SW. Chen C, et al. Among authors: lowe sw. Cancer Cell. 2014 May 12;25(5):652-65. doi: 10.1016/j.ccr.2014.03.016. Epub 2014 May 1. Cancer Cell. 2014. PMID: 24794707 Free PMC article.
p53-dependent Nestin regulation links tumor suppression to cellular plasticity in liver cancer.
Tschaharganeh DF, Xue W, Calvisi DF, Evert M, Michurina TV, Dow LE, Banito A, Katz SF, Kastenhuber ER, Weissmueller S, Huang CH, Lechel A, Andersen JB, Capper D, Zender L, Longerich T, Enikolopov G, Lowe SW. Tschaharganeh DF, et al. Among authors: lowe sw. Cell. 2014 Jul 31;158(3):579-92. doi: 10.1016/j.cell.2014.05.051. Cell. 2014. PMID: 25083869 Free PMC article.
Imaging of Liver Tumors Using Surface-Enhanced Raman Scattering Nanoparticles.
Andreou C, Neuschmelting V, Tschaharganeh DF, Huang CH, Oseledchyk A, Iacono P, Karabeber H, Colen RR, Mannelli L, Lowe SW, Kircher MF. Andreou C, et al. Among authors: lowe sw. ACS Nano. 2016 May 24;10(5):5015-26. doi: 10.1021/acsnano.5b07200. Epub 2016 May 10. ACS Nano. 2016. PMID: 27078225 Free PMC article.
BRD4 Connects Enhancer Remodeling to Senescence Immune Surveillance.
Tasdemir N, Banito A, Roe JS, Alonso-Curbelo D, Camiolo M, Tschaharganeh DF, Huang CH, Aksoy O, Bolden JE, Chen CC, Fennell M, Thapar V, Chicas A, Vakoc CR, Lowe SW. Tasdemir N, et al. Among authors: lowe sw. Cancer Discov. 2016 Jun;6(6):612-29. doi: 10.1158/2159-8290.CD-16-0217. Epub 2016 Apr 20. Cancer Discov. 2016. PMID: 27099234 Free PMC article.
A Pipeline for Drug Target Identification and Validation.
Manchado E, Huang CH, Tasdemir N, Tschaharganeh DF, Wilkinson JE, Lowe SW. Manchado E, et al. Among authors: lowe sw. Cold Spring Harb Symp Quant Biol. 2016;81:257-267. doi: 10.1101/sqb.2016.81.031096. Epub 2017 Jan 5. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28057848 Free PMC article. Review.
SOX2 promotes lineage plasticity and antiandrogen resistance in TP53- and RB1-deficient prostate cancer.
Mu P, Zhang Z, Benelli M, Karthaus WR, Hoover E, Chen CC, Wongvipat J, Ku SY, Gao D, Cao Z, Shah N, Adams EJ, Abida W, Watson PA, Prandi D, Huang CH, de Stanchina E, Lowe SW, Ellis L, Beltran H, Rubin MA, Goodrich DW, Demichelis F, Sawyers CL. Mu P, et al. Among authors: lowe sw. Science. 2017 Jan 6;355(6320):84-88. doi: 10.1126/science.aah4307. Science. 2017. PMID: 28059768 Free PMC article.
Histone Acetyltransferase Activity of MOF Is Required for MLL-AF9 Leukemogenesis.
Valerio DG, Xu H, Chen CW, Hoshii T, Eisold ME, Delaney C, Cusan M, Deshpande AJ, Huang CH, Lujambio A, Zheng YG, Zuber J, Pandita TK, Lowe SW, Armstrong SA. Valerio DG, et al. Among authors: lowe sw. Cancer Res. 2017 Apr 1;77(7):1753-1762. doi: 10.1158/0008-5472.CAN-16-2374. Epub 2017 Feb 15. Cancer Res. 2017. PMID: 28202522 Free PMC article.
Prediction of potent shRNAs with a sequential classification algorithm.
Pelossof R, Fairchild L, Huang CH, Widmer C, Sreedharan VT, Sinha N, Lai DY, Guan Y, Premsrirut PK, Tschaharganeh DF, Hoffmann T, Thapar V, Xiang Q, Garippa RJ, Rätsch G, Zuber J, Lowe SW, Leslie CS, Fellmann C. Pelossof R, et al. Among authors: lowe sw. Nat Biotechnol. 2017 Apr;35(4):350-353. doi: 10.1038/nbt.3807. Epub 2017 Mar 6. Nat Biotechnol. 2017. PMID: 28263295 Free PMC article.
370 results