Lowe SW - Search Results

1

A Pipeline for Drug Target Identification and Validation.

Manchado E, Huang CH, Tasdemir N, Tschaharganeh DF, Wilkinson JE, Lowe SW. Manchado E, et al. Among authors: lowe sw. Cold Spring Harb Symp Quant Biol. 2016;81:257-267. doi: 10.1101/sqb.2016.81.031096. Epub 2017 Jan 5. Cold Spring Harb Symp Quant Biol. 2016. PMID: 28057848 Free PMC article. Review.

2

DNA damage responses and chemosensitivity in the E mu-myc mouse lymphoma model.

Schmitt CA, Wallace-Brodeur RR, Rosenthal CT, McCurrach ME, Lowe SW. Schmitt CA, et al. Among authors: lowe sw. Cold Spring Harb Symp Quant Biol. 2000;65:499-510. doi: 10.1101/sqb.2000.65.499. Cold Spring Harb Symp Quant Biol. 2000. PMID: 12760067 No abstract available.

3

Probing tumor phenotypes using stable and regulated synthetic microRNA precursors.

Dickins RA, Hemann MT, Zilfou JT, Simpson DR, Ibarra I, Hannon GJ, Lowe SW. Dickins RA, et al. Among authors: lowe sw. Nat Genet. 2005 Nov;37(11):1289-95. doi: 10.1038/ng1651. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200064

4

Generation and analysis of genetically defined liver carcinomas derived from bipotential liver progenitors.

Zender L, Xue W, Cordón-Cardo C, Hannon GJ, Lucito R, Powers S, Flemming P, Spector MS, Lowe SW. Zender L, et al. Among authors: lowe sw. Cold Spring Harb Symp Quant Biol. 2005;70:251-61. doi: 10.1101/sqb.2005.70.059. Cold Spring Harb Symp Quant Biol. 2005. PMID: 16869761 Free PMC article.

5

Implications of cellular senescence in tissue damage response, tumor suppression, and stem cell biology.

Krizhanovsky V, Xue W, Zender L, Yon M, Hernando E, Lowe SW. Krizhanovsky V, et al. Among authors: lowe sw. Cold Spring Harb Symp Quant Biol. 2008;73:513-22. doi: 10.1101/sqb.2008.73.048. Epub 2009 Jan 15. Cold Spring Harb Symp Quant Biol. 2008. PMID: 19150958 Free PMC article. Review.

6

Functional identification of tumor-suppressor genes through an in vivo RNA interference screen in a mouse lymphoma model.

Bric A, Miething C, Bialucha CU, Scuoppo C, Zender L, Krasnitz A, Xuan Z, Zuber J, Wigler M, Hicks J, McCombie RW, Hemann MT, Hannon GJ, Powers S, Lowe SW. Bric A, et al. Among authors: lowe sw. Cancer Cell. 2009 Oct 6;16(4):324-35. doi: 10.1016/j.ccr.2009.08.015. Cancer Cell. 2009. PMID: 19800577 Free PMC article.

7

Toolkit for evaluating genes required for proliferation and survival using tetracycline-regulated RNAi.

Zuber J, McJunkin K, Fellmann C, Dow LE, Taylor MJ, Hannon GJ, Lowe SW. Zuber J, et al. Among authors: lowe sw. Nat Biotechnol. 2011 Jan;29(1):79-83. doi: 10.1038/nbt.1720. Epub 2010 Dec 5. Nat Biotechnol. 2011. PMID: 21131983 Free PMC article.

8

Functional identification of optimized RNAi triggers using a massively parallel sensor assay.

Fellmann C, Zuber J, McJunkin K, Chang K, Malone CD, Dickins RA, Xu Q, Hengartner MO, Elledge SJ, Hannon GJ, Lowe SW. Fellmann C, et al. Among authors: lowe sw. Mol Cell. 2011 Mar 18;41(6):733-46. doi: 10.1016/j.molcel.2011.02.008. Epub 2011 Feb 25. Mol Cell. 2011. PMID: 21353615 Free PMC article.

9

A rapid and scalable system for studying gene function in mice using conditional RNA interference.

Premsrirut PK, Dow LE, Kim SY, Camiolo M, Malone CD, Miething C, Scuoppo C, Zuber J, Dickins RA, Kogan SC, Shroyer KR, Sordella R, Hannon GJ, Lowe SW. Premsrirut PK, et al. Among authors: lowe sw. Cell. 2011 Apr 1;145(1):145-58. doi: 10.1016/j.cell.2011.03.012. Cell. 2011. PMID: 21458673 Free PMC article.

10

RNAi screen identifies Brd4 as a therapeutic target in acute myeloid leukaemia.

Zuber J, Shi J, Wang E, Rappaport AR, Herrmann H, Sison EA, Magoon D, Qi J, Blatt K, Wunderlich M, Taylor MJ, Johns C, Chicas A, Mulloy JC, Kogan SC, Brown P, Valent P, Bradner JE, Lowe SW, Vakoc CR. Zuber J, et al. Among authors: lowe sw. Nature. 2011 Aug 3;478(7370):524-8. doi: 10.1038/nature10334. Nature. 2011. PMID: 21814200 Free PMC article.

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