Low BC - Search Results

1

The scaffold RhoGAP protein ARHGAP8/BPGAP1 synchronizes Rac and Rho signaling to facilitate cell migration.

Wong DCP, Pan CQ, Er SY, Thivakar T, Rachel TZY, Seah SH, Chua PJ, Jiang T, Chew TW, Chaudhuri PK, Mukherjee S, Salim A, Aye TA, Koh CG, Lim CT, Tan PH, Bay BH, Ridley AJ, Low BC. Wong DCP, et al. Among authors: low bc. Mol Biol Cell. 2023 Mar 1;34(3):ar13. doi: 10.1091/mbc.E21-03-0099. Epub 2023 Jan 4. Mol Biol Cell. 2023. PMID: 36598812 Free PMC article.

2

BPGAP1 interacts with cortactin and facilitates its translocation to cell periphery for enhanced cell migration.

Lua BL, Low BC. Lua BL, et al. Among authors: low bc. Mol Biol Cell. 2004 Jun;15(6):2873-83. doi: 10.1091/mbc.e04-02-0141. Epub 2004 Apr 2. Mol Biol Cell. 2004. PMID: 15064355 Free PMC article.

3

Activation of EGF receptor endocytosis and ERK1/2 signaling by BPGAP1 requires direct interaction with EEN/endophilin II and a functional RhoGAP domain.

Lua BL, Low BC. Lua BL, et al. Among authors: low bc. J Cell Sci. 2005 Jun 15;118(Pt 12):2707-21. doi: 10.1242/jcs.02383. J Cell Sci. 2005. PMID: 15944398

4

Active Mek2 as a regulatory scaffold that promotes Pin1 binding to BPGAP1 to suppress BPGAP1-induced acute Erk activation and cell migration.

Pan CQ, Liou YC, Low BC. Pan CQ, et al. Among authors: low bc. J Cell Sci. 2010 Mar 15;123(Pt 6):903-16. doi: 10.1242/jcs.064162. Epub 2010 Feb 23. J Cell Sci. 2010. PMID: 20179103

5

The BNIP-2 and Cdc42GAP homology (BCH) domain of p50RhoGAP/Cdc42GAP sequesters RhoA from inactivation by the adjacent GTPase-activating protein domain.

Zhou YT, Chew LL, Lin SC, Low BC. Zhou YT, et al. Among authors: low bc. Mol Biol Cell. 2010 Sep 15;21(18):3232-46. doi: 10.1091/mbc.E09-05-0408. Epub 2010 Jul 21. Mol Biol Cell. 2010. PMID: 20660160 Free PMC article.

6

Simulating EGFR-ERK signaling control by scaffold proteins KSR and MP1 reveals differential ligand-sensitivity co-regulated by Cbl-CIN85 and endophilin.

Huang L, Pan CQ, Li B, Tucker-Kellogg L, Tidor B, Chen Y, Low BC. Huang L, et al. Among authors: low bc. PLoS One. 2011;6(8):e22933. doi: 10.1371/journal.pone.0022933. Epub 2011 Aug 1. PLoS One. 2011. PMID: 21829671 Free PMC article.

7

Structural basis for the allosteric inhibitory mechanism of human kidney-type glutaminase (KGA) and its regulation by Raf-Mek-Erk signaling in cancer cell metabolism.

Thangavelu K, Pan CQ, Karlberg T, Balaji G, Uttamchandani M, Suresh V, Schüler H, Low BC, Sivaraman J. Thangavelu K, et al. Among authors: low bc. Proc Natl Acad Sci U S A. 2012 May 15;109(20):7705-10. doi: 10.1073/pnas.1116573109. Epub 2012 Apr 26. Proc Natl Acad Sci U S A. 2012. PMID: 22538822 Free PMC article.

8

Functional plasticity of the BNIP-2 and Cdc42GAP Homology (BCH) domain in cell signaling and cell dynamics.

Pan CQ, Low BC. Pan CQ, et al. Among authors: low bc. FEBS Lett. 2012 Aug 14;586(17):2674-91. doi: 10.1016/j.febslet.2012.04.023. Epub 2012 Apr 21. FEBS Lett. 2012. PMID: 22710163 Free article. Review.

9

Modularity and functional plasticity of scaffold proteins as p(l)acemakers in cell signaling.

Pan CQ, Sudol M, Sheetz M, Low BC. Pan CQ, et al. Among authors: low bc. Cell Signal. 2012 Nov;24(11):2143-65. doi: 10.1016/j.cellsig.2012.06.002. Epub 2012 Jun 25. Cell Signal. 2012. PMID: 22743133 Free article. Review.

10

SmgGDS antagonizes BPGAP1-induced Ras/ERK activation and neuritogenesis in PC12 cell differentiation.

Ravichandran A, Low BC. Ravichandran A, et al. Among authors: low bc. Mol Biol Cell. 2013 Jan;24(2):145-56. doi: 10.1091/mbc.E12-04-0300. Epub 2012 Nov 14. Mol Biol Cell. 2013. PMID: 23155002 Free PMC article.

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