Louisse J - Search Results

1

A Computational Understanding of Inter-Individual Variability in CYP2D6 Activity to Investigate the Impact of Missense Mutations on Ochratoxin A Metabolism.

Dorne JLCM, Cirlini M, Louisse J, Pedroni L, Galaverna G, Dellafiora L. Dorne JLCM, et al. Among authors: louisse j. Toxins (Basel). 2022 Mar 14;14(3):207. doi: 10.3390/toxins14030207. Toxins (Basel). 2022. PMID: 35324704 Free PMC article.

2

Next generation physiologically based kinetic (NG-PBK) models in support of regulatory decision making.

Paini A, Leonard JA, Joossens E, Bessems JGM, Desalegn A, Dorne JL, Gosling JP, Heringa MB, Klaric M, Kliment T, Kramer NI, Loizou G, Louisse J, Lumen A, Madden JC, Patterson EA, Proença S, Punt A, Setzer RW, Suciu N, Troutman J, Yoon M, Worth A, Tan YM. Paini A, et al. Among authors: louisse j. Comput Toxicol. 2019 Feb;9:61-72. doi: 10.1016/j.comtox.2018.11.002. Comput Toxicol. 2019. PMID: 31008414 Free PMC article. Review.

3

Investigating the interaction between organic anion transporter 1 and ochratoxin A: An in silico structural study to depict early molecular events of substrate recruitment and the impact of single point mutations.

Louisse J, Dorne JLCM, Dellafiora L. Louisse J, et al. Toxicol Lett. 2022 Feb 1;355:19-30. doi: 10.1016/j.toxlet.2021.11.001. Epub 2021 Nov 5. Toxicol Lett. 2022. PMID: 34748852 Free article.

4

Perfluoroalkyl substances (PFASs) are substrates of the renal human organic anion transporter 4 (OAT4).

Louisse J, Dellafiora L, van den Heuvel JJMW, Rijkers D, Leenders L, Dorne JCM, Punt A, Russel FGM, Koenderink JB. Louisse J, et al. Arch Toxicol. 2023 Mar;97(3):685-696. doi: 10.1007/s00204-022-03428-6. Epub 2022 Nov 27. Arch Toxicol. 2023. PMID: 36436016 Free PMC article.

5

A Computational Inter-Species Study on Safrole Phase I Metabolism-Dependent Bioactivation: A Mechanistic Insight into the Study of Possible Differences among Species.

Pedroni L, Louisse J, Punt A, Dorne JLCM, Dall'Asta C, Dellafiora L. Pedroni L, et al. Among authors: louisse j. Toxins (Basel). 2023 Jan 18;15(2):94. doi: 10.3390/toxins15020094. Toxins (Basel). 2023. PMID: 36828409 Free PMC article.

6

A computational study on the biotransformation of alkenylbenzenes by a selection of CYPs: Reflections on their possible bioactivation.

Pedroni L, Louisse J, Dorne JCM, Dall'Asta C, Dellafiora L. Pedroni L, et al. Among authors: louisse j. Toxicology. 2023 Apr;488:153471. doi: 10.1016/j.tox.2023.153471. Epub 2023 Feb 28. Toxicology. 2023. PMID: 36863505 Free article.

7

Providing Biological Plausibility for Exposure-Health Relationships for the Mycotoxins Deoxynivalenol (DON) and Fumonisin B1 (FB1) in Humans Using the AOP Framework.

van den Brand AD, Bajard L, Steffensen IL, Brantsæter AL, Dirven HAAM, Louisse J, Peijnenburg A, Ndaw S, Mantovani A, De Santis B, Mengelers MJB. van den Brand AD, et al. Among authors: louisse j. Toxins (Basel). 2022 Apr 13;14(4):279. doi: 10.3390/toxins14040279. Toxins (Basel). 2022. PMID: 35448888 Free PMC article.

8

Comparison of gene expression and biotransformation activity of HepaRG cells under static and dynamic culture conditions.

Duivenvoorde LPM, Louisse J, Pinckaers NET, Nguyen T, van der Zande M. Duivenvoorde LPM, et al. Among authors: louisse j. Sci Rep. 2021 May 14;11(1):10327. doi: 10.1038/s41598-021-89710-6. Sci Rep. 2021. PMID: 33990636 Free PMC article.

9

Metabolites in the regulatory risk assessment of pesticides in the EU.

Pelkonen O, Abass K, Parra Morte JM, Panzarea M, Testai E, Rudaz S, Louisse J, Gundert-Remy U, Wolterink G, Jean-Lou Cm D, Coecke S, Bernasconi C. Pelkonen O, et al. Among authors: louisse j. Front Toxicol. 2023 Dec 19;5:1304885. doi: 10.3389/ftox.2023.1304885. eCollection 2023. Front Toxicol. 2023. PMID: 38188093 Free PMC article. Review.

10

Determination of in vitro immunotoxic potencies of a series of perfluoralkylsubstances (PFASs) in human Namalwa B lymphocyte and human Jurkat T lymphocyte cells.

Janssen AWF, Jansen Holleboom W, Rijkers D, Louisse J, Hoekstra SA, Schild S, Vrolijk MF, Hoogenboom RLAP, Beekmann K. Janssen AWF, et al. Among authors: louisse j. Front Toxicol. 2024 Mar 14;6:1347965. doi: 10.3389/ftox.2024.1347965. eCollection 2024. Front Toxicol. 2024. PMID: 38549690 Free PMC article.

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