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The New Antitumor Drug ABTL0812 Inhibits the Akt/mTORC1 Axis by Upregulating Tribbles-3 Pseudokinase.
Erazo T, Lorente M, López-Plana A, Muñoz-Guardiola P, Fernández-Nogueira P, García-Martínez JA, Bragado P, Fuster G, Salazar M, Espadaler J, Hernández-Losa J, Bayascas JR, Cortal M, Vidal L, Gascón P, Gómez-Ferreria M, Alfón J, Velasco G, Domènech C, Lizcano JM. Erazo T, et al. Among authors: lorente m. Clin Cancer Res. 2016 May 15;22(10):2508-19. doi: 10.1158/1078-0432.CCR-15-1808. Epub 2015 Dec 15. Clin Cancer Res. 2016. PMID: 26671995 Free article. Clinical Trial.
The stress-regulated protein p8 mediates cannabinoid-induced apoptosis of tumor cells.
Carracedo A, Lorente M, Egia A, Blázquez C, García S, Giroux V, Malicet C, Villuendas R, Gironella M, González-Feria L, Piris MA, Iovanna JL, Guzmán M, Velasco G. Carracedo A, et al. Among authors: lorente m. Cancer Cell. 2006 Apr;9(4):301-12. doi: 10.1016/j.ccr.2006.03.005. Cancer Cell. 2006. PMID: 16616335 Free article.
Cannabinoids and gliomas.
Velasco G, Carracedo A, Blázquez C, Lorente M, Aguado T, Haro A, Sánchez C, Galve-Roperh I, Guzmán M. Velasco G, et al. Among authors: lorente m. Mol Neurobiol. 2007 Aug;36(1):60-7. doi: 10.1007/s12035-007-0002-5. Epub 2007 Jun 28. Mol Neurobiol. 2007. PMID: 17952650 Review.
Cannabinoid action induces autophagy-mediated cell death through stimulation of ER stress in human glioma cells.
Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Lorente M, Egia A, Vázquez P, Blázquez C, Torres S, García S, Nowak J, Fimia GM, Piacentini M, Cecconi F, Pandolfi PP, González-Feria L, Iovanna JL, Guzmán M, Boya P, Velasco G. Salazar M, et al. Among authors: lorente m. J Clin Invest. 2009 May;119(5):1359-72. doi: 10.1172/jci37948. J Clin Invest. 2009. PMID: 19425170 Free PMC article.
TRB3 links ER stress to autophagy in cannabinoid anti-tumoral action.
Salazar M, Carracedo A, Salanueva IJ, Hernández-Tiedra S, Egia A, Lorente M, Vázquez P, Torres S, Iovanna JL, Guzmán M, Boya P, Velasco G. Salazar M, et al. Among authors: lorente m. Autophagy. 2009 Oct;5(7):1048-9. doi: 10.4161/auto.5.7.9508. Epub 2009 Oct 14. Autophagy. 2009. PMID: 19652543 No abstract available.
282 results