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Page 1
Single Stranded Fully Modified-Phosphorothioate Oligonucleotides can Induce Structured Nuclear Inclusions, Alter Nuclear Protein Localization and Disturb the Transcriptome In Vitro.
Flynn LL, Li R, Pitout IL, Aung-Htut MT, Larcher LM, Cooper JAL, Greer KL, Hubbard A, Griffiths L, Bond CS, Wilton SD, Fox AH, Fletcher S. Flynn LL, et al. Front Genet. 2022 Apr 6;13:791416. doi: 10.3389/fgene.2022.791416. eCollection 2022. Front Genet. 2022. PMID: 35464859 Free PMC article.
Novel STMN2 Variant Linked to Amyotrophic Lateral Sclerosis Risk and Clinical Phenotype.
Theunissen F, Anderton RS, Mastaglia FL, Flynn LL, Winter SJ, James I, Bedlack R, Hodgetts S, Fletcher S, Wilton SD, Laing NG, MacShane M, Needham M, Saunders A, Mackay-Sim A, Melamed Z, Ravits J, Cleveland DW, Akkari PA. Theunissen F, et al. Among authors: flynn ll. Front Aging Neurosci. 2021 Mar 26;13:658226. doi: 10.3389/fnagi.2021.658226. eCollection 2021. Front Aging Neurosci. 2021. PMID: 33841129 Free PMC article.
Disease-modifying effects of an SCAF4 structural variant in a predominantly SOD1 ALS cohort.
Pytte J, Flynn LL, Anderton RS, Mastaglia FL, Theunissen F, James I, Pfaff A, Koks S, Saunders AM, Bedlack R, Burns DK, Lutz MW, Siddique N, Siddique T, Roses AD, Akkari PA. Pytte J, et al. Among authors: flynn ll. Neurol Genet. 2020 Jul 1;6(4):e470. doi: 10.1212/NXG.0000000000000470. eCollection 2020 Aug. Neurol Genet. 2020. PMID: 32754644 Free PMC article.
Structural Variants May Be a Source of Missing Heritability in sALS.
Theunissen F, Flynn LL, Anderton RS, Mastaglia F, Pytte J, Jiang L, Hodgetts S, Burns DK, Saunders A, Fletcher S, Wilton SD, Akkari PA. Theunissen F, et al. Among authors: flynn ll. Front Neurosci. 2020 Jan 31;14:47. doi: 10.3389/fnins.2020.00047. eCollection 2020. Front Neurosci. 2020. PMID: 32082115 Free PMC article.
ALS Genetics, Mechanisms, and Therapeutics: Where Are We Now?
Mejzini R, Flynn LL, Pitout IL, Fletcher S, Wilton SD, Akkari PA. Mejzini R, et al. Among authors: flynn ll. Front Neurosci. 2019 Dec 6;13:1310. doi: 10.3389/fnins.2019.01310. eCollection 2019. Front Neurosci. 2019. PMID: 31866818 Free PMC article. Review.
12 results