Loregger A - Search Results

1

SPRING is a Dedicated Licensing Factor for SREBP-Specific Activation by S1P.

Hendrix S, Tan JME, Ndoj K, Kingma J, Valiloo M, Zijlstra LF, Ottenhoff R, Seidah NG, Loregger A, Kober DL, Zelcer N. Hendrix S, et al. Among authors: loregger a. Mol Cell Biol. 2024 May 15:1-15. doi: 10.1080/10985549.2024.2348711. Online ahead of print. Mol Cell Biol. 2024. PMID: 38747374

2

Decoding Heterogenous Single-cell Perturbation Responses.

Song B, Liu D, Dai W, McMyn N, Wang Q, Yang D, Krejci A, Vasilyev A, Untermoser N, Loregger A, Song D, Williams B, Rosen B, Cheng X, Chao L, Kale HT, Zhang H, Diao Y, Bürckstümmer T, Siliciano JM, Li JJ, Siliciano R, Huangfu D, Li W. Song B, et al. Among authors: loregger a. bioRxiv [Preprint]. 2023 Nov 29:2023.10.30.564796. doi: 10.1101/2023.10.30.564796. bioRxiv. 2023. PMID: 37961332 Free PMC article. Preprint.

3

Hepatic SREBP signaling requires SPRING to govern systemic lipid metabolism in mice and humans.

Hendrix S, Kingma J, Ottenhoff R, Valiloo M, Svecla M, Zijlstra LF, Sachdev V, Kovac K, Levels JHM, Jongejan A, de Boer JF, Kuipers F, Rimbert A, Norata GD, Loregger A, Zelcer N. Hendrix S, et al. Among authors: loregger a. Nat Commun. 2023 Aug 25;14(1):5181. doi: 10.1038/s41467-023-40943-1. Nat Commun. 2023. PMID: 37626055 Free PMC article.

4

The MARCH6-SQLE Axis Controls Endothelial Cholesterol Homeostasis and Angiogenic Sprouting.

Tan JME, van der Stoel MM, van den Berg M, van Loon NM, Moeton M, Scholl E, van der Wel NN, Kovačević I, Hordijk PL, Loregger A, Huveneers S, Zelcer N. Tan JME, et al. Among authors: loregger a. Cell Rep. 2020 Aug 4;32(5):107944. doi: 10.1016/j.celrep.2020.107944. Cell Rep. 2020. PMID: 32755570 Free article.

5

Haploid genetic screens identify SPRING/C12ORF49 as a determinant of SREBP signaling and cholesterol metabolism.

Loregger A, Raaben M, Nieuwenhuis J, Tan JME, Jae LT, van den Hengel LG, Hendrix S, van den Berg M, Scheij S, Song JY, Huijbers IJ, Kroese LJ, Ottenhoff R, van Weeghel M, van de Sluis B, Brummelkamp T, Zelcer N. Loregger A, et al. Nat Commun. 2020 Feb 28;11(1):1128. doi: 10.1038/s41467-020-14811-1. Nat Commun. 2020. PMID: 32111832 Free PMC article.

6

Industrial Trans Fatty Acids Stimulate SREBP2-Mediated Cholesterogenesis and Promote Non-Alcoholic Fatty Liver Disease.

Oteng AB, Loregger A, van Weeghel M, Zelcer N, Kersten S. Oteng AB, et al. Among authors: loregger a. Mol Nutr Food Res. 2019 Oct;63(19):e1900385. doi: 10.1002/mnfr.201900385. Epub 2019 Aug 7. Mol Nutr Food Res. 2019. PMID: 31327168 Free PMC article.

7

N-Glycosylation Defects in Humans Lower Low-Density Lipoprotein Cholesterol Through Increased Low-Density Lipoprotein Receptor Expression.

van den Boogert MAW, Larsen LE, Ali L, Kuil SD, Chong PLW, Loregger A, Kroon J, Schnitzler JG, Schimmel AWM, Peter J, Levels JHM, Steenbergen G, Morava E, Dallinga-Thie GM, Wevers RA, Kuivenhoven JA, Hand NJ, Zelcer N, Rader DJ, Stroes ESG, Lefeber DJ, Holleboom AG. van den Boogert MAW, et al. Among authors: loregger a. Circulation. 2019 Jul 23;140(4):280-292. doi: 10.1161/CIRCULATIONAHA.118.036484. Epub 2019 May 23. Circulation. 2019. PMID: 31117816

8

Differential use of E2 ubiquitin conjugating enzymes for regulated degradation of the rate-limiting enzymes HMGCR and SQLE in cholesterol biosynthesis.

Tan JME, Cook ECL, van den Berg M, Scheij S, Zelcer N, Loregger A. Tan JME, et al. Among authors: loregger a. Atherosclerosis. 2019 Feb;281:137-142. doi: 10.1016/j.atherosclerosis.2018.12.008. Epub 2018 Dec 23. Atherosclerosis. 2019. PMID: 30658189 Free article.

9

FBXW7 regulates endothelial barrier function by suppression of the cholesterol synthesis pathway and prenylation of RhoB.

Pronk MCA, Majolée J, Loregger A, van Bezu JSM, Zelcer N, Hordijk PL, Kovačević I. Pronk MCA, et al. Among authors: loregger a. Mol Biol Cell. 2019 Mar 1;30(5):607-621. doi: 10.1091/mbc.E18-04-0259. Epub 2019 Jan 2. Mol Biol Cell. 2019. PMID: 30601691 Free PMC article.

10

Retraction Note: Liver X receptors constrain tumor development and metastasis dissemination in PTEN-deficient prostate cancer.

Alioui A, Dufour J, Leoni V, Loregger A, Moeton M, Iuliano L, Zerbinati C, Septier A, Val P, Fouache A, Russo V, Volle DH, Lobaccaro JA, Zelcer N, Baron S. Alioui A, et al. Among authors: loregger a. Nat Commun. 2018 Jul 4;9(1):2660. doi: 10.1038/s41467-018-04653-3. Nat Commun. 2018. PMID: 29973583 Free PMC article.

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