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Immune checkpoint inhibitor-induced colitis is mediated by polyfunctional lymphocytes and is dependent on an IL23/IFNγ axis.
Lo JW, Cozzetto D, Alexander JL, Danckert NP, Madgwick M, Knox N, Sieh JYX, Olbei M, Liu Z, Ibraheim H, Blanco JM, Kudo H, Seoane RC, Possamai LA, Goldin R, Marchesi J, Korcsmaros T, Lord GM, Powell N. Lo JW, et al. Among authors: lord gm. Nat Commun. 2023 Oct 23;14(1):6719. doi: 10.1038/s41467-023-41798-2. Nat Commun. 2023. PMID: 37872166 Free PMC article.
Interleukin-22 regulates neutrophil recruitment in ulcerative colitis and is associated with resistance to ustekinumab therapy.
Pavlidis P, Tsakmaki A, Pantazi E, Li K, Cozzetto D, Digby-Bell J, Yang F, Lo JW, Alberts E, Sa ACC, Niazi U, Friedman J, Long AK, Ding Y, Carey CD, Lamb C, Saqi M, Madgwick M, Gul L, Treveil A, Korcsmaros T, Macdonald TT, Lord GM, Bewick G, Powell N. Pavlidis P, et al. Among authors: lord gm. Nat Commun. 2022 Oct 3;13(1):5820. doi: 10.1038/s41467-022-33331-8. Nat Commun. 2022. PMID: 36192482 Free PMC article.
T-Bet Controls Cellularity of Intestinal Group 3 Innate Lymphoid Cells.
Schroeder JH, Meissl K, Hromadová D, Lo JW, Neves JF, Howard JK, Helmby H, Powell N, Strobl B, Lord GM. Schroeder JH, et al. Among authors: lord gm. Front Immunol. 2021 Feb 2;11:623324. doi: 10.3389/fimmu.2020.623324. eCollection 2020. Front Immunol. 2021. PMID: 33603753 Free PMC article.
Interleukin-22 orchestrates a pathological endoplasmic reticulum stress response transcriptional programme in colonic epithelial cells.
Powell N, Pantazi E, Pavlidis P, Tsakmaki A, Li K, Yang F, Parker A, Pin C, Cozzetto D, Minns D, Stolarczyk E, Saveljeva S, Mohamed R, Lavender P, Afzali B, Digby-Bell J, Tjir-Li T, Kaser A, Friedman J, MacDonald TT, Bewick GA, Lord GM. Powell N, et al. Among authors: lord gm. Gut. 2020 Mar;69(3):578-590. doi: 10.1136/gutjnl-2019-318483. Epub 2019 Dec 2. Gut. 2020. PMID: 31792136 Free PMC article. Review.
Sustained Post-Developmental T-Bet Expression Is Critical for the Maintenance of Type One Innate Lymphoid Cells In Vivo.
Schroeder JH, Roberts LB, Meissl K, Lo JW, Hromadová D, Hayes K, Zabinski T, Read E, Moreira Heliodoro C, Reis R, Howard JK, Grencis RK, Neves JF, Strobl B, Lord GM. Schroeder JH, et al. Among authors: lord gm. Front Immunol. 2021 Oct 29;12:760198. doi: 10.3389/fimmu.2021.760198. eCollection 2021. Front Immunol. 2021. PMID: 34795671 Free PMC article.
143 results