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Brain α7 Nicotinic Acetylcholine Receptor Assembly Requires NACHO.
Gu S, Matta JA, Lord B, Harrington AW, Sutton SW, Davini WB, Bredt DS. Gu S, et al. Among authors: lord b. Neuron. 2016 Mar 2;89(5):948-55. doi: 10.1016/j.neuron.2016.01.018. Epub 2016 Feb 11. Neuron. 2016. PMID: 26875622 Free article.
2-Aryloxymethylmorpholine histamine H(3) antagonists.
Letavic MA, Keith JM, Ly KS, Bonaventure P, Feinstein MA, Lord B, Miller KL, Motley ST, Nepomuceno D, Sutton SW, Carruthers NI. Letavic MA, et al. Among authors: lord b. Bioorg Med Chem Lett. 2008 Nov 1;18(21):5796-9. doi: 10.1016/j.bmcl.2008.09.077. Epub 2008 Sep 24. Bioorg Med Chem Lett. 2008. PMID: 18922693
Characterization of JNJ-42847922, a Selective Orexin-2 Receptor Antagonist, as a Clinical Candidate for the Treatment of Insomnia.
Bonaventure P, Shelton J, Yun S, Nepomuceno D, Sutton S, Aluisio L, Fraser I, Lord B, Shoblock J, Welty N, Chaplan SR, Aguilar Z, Halter R, Ndifor A, Koudriakova T, Rizzolio M, Letavic M, Carruthers NI, Lovenberg T, Dugovic C. Bonaventure P, et al. Among authors: lord b. J Pharmacol Exp Ther. 2015 Sep;354(3):471-82. doi: 10.1124/jpet.115.225466. Epub 2015 Jul 15. J Pharmacol Exp Ther. 2015. PMID: 26177655
Discovery and Characterization of AMPA Receptor Modulators Selective for TARP-γ8.
Maher MP, Wu N, Ravula S, Ameriks MK, Savall BM, Liu C, Lord B, Wyatt RM, Matta JA, Dugovic C, Yun S, Ver Donck L, Steckler T, Wickenden AD, Carruthers NI, Lovenberg TW. Maher MP, et al. Among authors: lord b. J Pharmacol Exp Ther. 2016 May;357(2):394-414. doi: 10.1124/jpet.115.231712. Epub 2016 Mar 17. J Pharmacol Exp Ther. 2016. PMID: 26989142
Pharmacologic Characterization of JNJ-42226314, [1-(4-Fluorophenyl)indol-5-yl]-[3-[4-(thiazole-2-carbonyl)piperazin-1-yl]azetidin-1-yl]methanone, a Reversible, Selective, and Potent Monoacylglycerol Lipase Inhibitor.
Wyatt RM, Fraser I, Welty N, Lord B, Wennerholm M, Sutton S, Ameriks MK, Dugovic C, Yun S, White A, Nguyen L, Koudriakova T, Tian G, Suarez J, Szewczuk L, Bonnette W, Ahn K, Ghosh B, Flores CM, Connolly PJ, Zhu B, Macielag MJ, Brandt MR, Chevalier K, Zhang SP, Lovenberg T, Bonaventure P. Wyatt RM, et al. Among authors: lord b. J Pharmacol Exp Ther. 2020 Mar;372(3):339-353. doi: 10.1124/jpet.119.262139. Epub 2019 Dec 9. J Pharmacol Exp Ther. 2020. PMID: 31818916
Structure-Based Optimization of Selective and Brain Penetrant CK1δ Inhibitors for the Treatment of Circadian Disruptions.
McCarver S, Hanna L, Samant A, Thompson AA, Seierstad M, Saha A, Wu D, Lord B, Sutton SW, Shah V, Milligan CM, Wennerholm M, Shelton J, Lebold TP, Shireman BT. McCarver S, et al. Among authors: lord b. ACS Med Chem Lett. 2024 Mar 7;15(4):486-492. doi: 10.1021/acsmedchemlett.3c00523. eCollection 2024 Apr 11. ACS Med Chem Lett. 2024. PMID: 38628796
331 results