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ATM Regulates Differentiation of Myofibroblastic Cancer-Associated Fibroblasts and Can Be Targeted to Overcome Immunotherapy Resistance.
Mellone M, Piotrowska K, Venturi G, James L, Bzura A, Lopez MA, James S, Wang C, Ellis MJ, Hanley CJ, Buckingham JF, Cox KL, Hughes G, Valge-Archer V, King EV, Beers SA, Jaquet V, Jones GDD, Savelyeva N, Sayan E, Parsons JL, Durant S, Thomas GJ. Mellone M, et al. Among authors: lopez ma. Cancer Res. 2022 Dec 16;82(24):4571-4585. doi: 10.1158/0008-5472.CAN-22-0435. Cancer Res. 2022. PMID: 36353752 Free PMC article.
The ZEB2-dependent EMT transcriptional programme drives therapy resistance by activating nucleotide excision repair genes ERCC1 and ERCC4 in colorectal cancer.
Sreekumar R, Al-Saihati H, Emaduddin M, Moutasim K, Mellone M, Patel A, Kilic S, Cetin M, Erdemir S, Navio MS, Lopez MA, Curtis N, Yagci T, Primrose JN, Price BD, Berx G, Thomas GJ, Tulchinsky E, Mirnezami A, Sayan AE. Sreekumar R, et al. Among authors: lopez ma. Mol Oncol. 2021 Aug;15(8):2065-2083. doi: 10.1002/1878-0261.12965. Epub 2021 May 1. Mol Oncol. 2021. PMID: 33931939 Free PMC article.
Analysis of Immune Landscape in Pancreatic and Ileal Neuroendocrine Tumours Demonstrates an Immune Cold Tumour Microenvironment.
Tanno L, Naheed S, Dunbar J, Tod J, Lopez MA, Taylor J, Machado M, Green B, Ashton-Key M, Chee SJ, Wood O, Pearce NW, Thomas GJ, Friedmann PS, Cave J, Ottensmeier CH. Tanno L, et al. Among authors: lopez ma. Neuroendocrinology. 2022;112(4):370-383. doi: 10.1159/000517688. Epub 2021 Jun 22. Neuroendocrinology. 2022. PMID: 34157710
Single-cell analysis reveals prognostic fibroblast subpopulations linked to molecular and immunological subtypes of lung cancer.
Hanley CJ, Waise S, Ellis MJ, Lopez MA, Pun WY, Taylor J, Parker R, Kimbley LM, Chee SJ, Shaw EC, West J, Alzetani A, Woo E, Ottensmeier CH, Rose-Zerilli MJJ, Thomas GJ. Hanley CJ, et al. Among authors: lopez ma. Nat Commun. 2023 Jan 31;14(1):387. doi: 10.1038/s41467-023-35832-6. Nat Commun. 2023. PMID: 36720863 Free PMC article.
Long-read genome sequencing and variant reanalysis increase diagnostic yield in neurodevelopmental disorders.
Hiatt SM, Lawlor JMJ, Handley LH, Latner DR, Bonnstetter ZT, Finnila CR, Thompson ML, Boston LB, Williams M, Nunez IR, Jenkins J, Kelley WV, Bebin EM, Lopez MA, Hurst ACE, Korf BR, Schmutz J, Grimwood J, Cooper GM. Hiatt SM, et al. Among authors: lopez ma. medRxiv [Preprint]. 2024 Mar 26:2024.03.22.24304633. doi: 10.1101/2024.03.22.24304633. medRxiv. 2024. PMID: 38585854 Free PMC article. Preprint.
Identifying drivers of cost in pediatric liver transplantation.
Sabapathy DG, Hosek K, Lam FW, Desai MS, Williams EA, Goss J, Raphael JL, Lopez MA. Sabapathy DG, et al. Among authors: lopez ma. Liver Transpl. 2024 Mar 27. doi: 10.1097/LVT.0000000000000367. Online ahead of print. Liver Transpl. 2024. PMID: 38535617
623 results