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Novel App knock-in mouse model shows key features of amyloid pathology and reveals profound metabolic dysregulation of microglia.
Xia D, Lianoglou S, Sandmann T, Calvert M, Suh JH, Thomsen E, Dugas J, Pizzo ME, DeVos SL, Earr TK, Lin CC, Davis S, Ha C, Leung AW, Nguyen H, Chau R, Yulyaningsih E, Lopez I, Solanoy H, Masoud ST, Liang CC, Lin K, Astarita G, Khoury N, Zuchero JY, Thorne RG, Shen K, Miller S, Palop JJ, Garceau D, Sasner M, Whitesell JD, Harris JA, Hummel S, Gnörich J, Wind K, Kunze L, Zatcepin A, Brendel M, Willem M, Haass C, Barnett D, Zimmer TS, Orr AG, Scearce-Levie K, Lewcock JW, Di Paolo G, Sanchez PE. Xia D, et al. Among authors: lopez i. Mol Neurodegener. 2022 Jun 11;17(1):41. doi: 10.1186/s13024-022-00547-7. Mol Neurodegener. 2022. PMID: 35690868 Free PMC article.
Behavioral and neural network abnormalities in human APP transgenic mice resemble those of App knock-in mice and are modulated by familial Alzheimer's disease mutations but not by inhibition of BACE1.
Johnson ECB, Ho K, Yu GQ, Das M, Sanchez PE, Djukic B, Lopez I, Yu X, Gill M, Zhang W, Paz JT, Palop JJ, Mucke L. Johnson ECB, et al. Among authors: lopez i. Mol Neurodegener. 2020 Sep 14;15(1):53. doi: 10.1186/s13024-020-00393-5. Mol Neurodegener. 2020. PMID: 32921309 Free PMC article.
Iduronate-2-sulfatase transport vehicle rescues behavioral and skeletal phenotypes in a mouse model of Hunter syndrome.
Arguello A, Meisner R, Thomsen ER, Nguyen HN, Ravi R, Simms J, Lo I, Speckart J, Holtzman J, Gill TM, Chan D, Cheng Y, Chiu CL, Dugas JC, Fang M, Lopez IA, Solanoy H, Tsogtbaatar B, Zhu Y, Bhalla A, Henne KR, Henry AG, Delucchi A, Costanzo S, Harris JM, Diaz D, Scearce-Levie K, Sanchez PE. Arguello A, et al. Among authors: lopez ia. JCI Insight. 2021 Oct 8;6(19):e145445. doi: 10.1172/jci.insight.145445. JCI Insight. 2021. PMID: 34622797 Free PMC article.
Tau Reduction Prevents Key Features of Autism in Mouse Models.
Tai C, Chang CW, Yu GQ, Lopez I, Yu X, Wang X, Guo W, Mucke L. Tai C, et al. Among authors: lopez i. Neuron. 2020 May 6;106(3):421-437.e11. doi: 10.1016/j.neuron.2020.01.038. Epub 2020 Mar 2. Neuron. 2020. PMID: 32126198 Free PMC article.
Knowledge, attitudes and perceptions of Latin American healthcare workers relating to antibiotic stewardship and antibiotic use: a cross-sectional multi-country study.
Fabre V, Cosgrove SE, Lessa FC, Patel TS, Reyes-Morales G, Aleman WR, Alvarez AA, Aquiles B, Arauz AB, Arguello F, Barberis MF, Barcan L, Bernachea MP, Bernan ML, Buitrago C, Del Carmen Bangher M, Castañeda X, Colque AM, Canton A, Contreras R, Correa S, Campero GC, Espinola L, Esquivel C, Ezcurra C, Falleroni LA, Fernandez J, Ferrari S, Frassone N, Cruz CG, Garzón MI, Quintero CHG, Gonzalez JA, Guaymas L, Guerrero-Toapanta F, Lambert S, Laplume D, Lazarte PR, Lemir CG, Lopez A, Lopez IL, Maldonado H, Martinez G, Maurizi DM, Melgar M, Mesplet F, Pertuz CM, Moreno C, Moya GL, Nuccetelli Y, Núñez G, Osuna C, Palacio B, Pellice F, Raffo C, Choto FR, Ricoy G, Rodriguez V, Romero F, Romero JJ, Russo ME, Sadino G, Sandoval N, Silva MG, Urueña AM, Reyes LV, Videla H, Valle M, Perez SVA, Vergara-Samur H, Villamandos S, Villarreal O, Viteri A, Warley E, Quiros RE. Fabre V, et al. Among authors: lopez il. Antimicrob Resist Infect Control. 2024 Apr 26;13(1):47. doi: 10.1186/s13756-024-01400-w. Antimicrob Resist Infect Control. 2024. PMID: 38664757 Free PMC article.
Trametinib sensitizes KRAS-mutant lung adenocarcinoma tumors to PD-1/PD-L1 axis blockade via Id1 downregulation.
Puyalto A, Rodríguez-Remírez M, López I, Macaya I, Guruceaga E, Olmedo M, Vilalta-Lacarra A, Welch C, Sandiego S, Vicent S, Valencia K, Calvo A, Pio R, Raez LE, Rolfo C, Ajona D, Gil-Bazo I. Puyalto A, et al. Among authors: lopez i. Mol Cancer. 2024 Apr 20;23(1):78. doi: 10.1186/s12943-024-01991-3. Mol Cancer. 2024. PMID: 38643157 Free PMC article.
1,073 results